Protein Alignment Nckx30C and Slc24a4

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_742164.2
• Gene: Slc24a4 / 238384
• MGIID: 2447362
• Length: 622
• Species: Mus musculus
• Alignment Length: 615
• Identity: 224/615 - (36%)
• Similarity: 329/615 - (53%)
• Gaps: 124/615 - (20%)

  Fly   309 NSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVA 373
            |.|......||.|||:.::.::|||:|||:|.:|||.|||||||:||||||:.|.|||.:::|||
Mouse    76 NCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVA 140

  Fly   374 GATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLFR 438
            ||||||||.|.||||.||||||::..|||:||||||||||||.:||:|.||:..|:.||||.:.|
Mouse   141 GATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCR 205

  Fly   439 DCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCVKKMITKNKVTRVRST 503
            |..:|::|::|||.|..|..|.|||.|:|..:|:.|:..||:|::::|.   ..||.|
Mouse   206 DSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMKYNMKMQTF---FTTKQK------- 260

  Fly   504 DQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGSTQTGAKF 568
                   :.||.:..|...:.|
Mouse   261 -------SIANGNPVSNELEDG------------------------------------------- 275

  Fly   569 RHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLK----------VLLDA---------TKPQRG- 613
                        :.|:||..|:.:..|  :..:|          |::|.         |.|:.|
Mouse   276 ------------NDLYDGSYDDPSVPL--LGQVKEKPPYGKTPVVMVDEILSSSPPKFTFPEAGL 326

  Fly   614 --------GATT--SAANHVKINLKETTLADRPNGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKF 668
                    |..|  ..|:.:.||.:: .|.:..||    ....|..:||..:.....|.::..:.
Mouse   327 RIMITNKFGPRTRLRMASRIIINERQ-RLINSANG----VNSKPLQNGRHENMENGNVPVENPED 386

  Fly   669 SIKAPEIEDEPEP------------LS-MAWPDTARKRLTYVLVAPLLVPMWLTLPDTRTPRGKR 720
            ..:..|.:..|:|            || .:.|:....:..:|...||:..:.:|:|:...||.::
Mouse   387 PQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEK 451

  Fly   721 FFPVTFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGD 785
            ||.||||.:.:|||.|||||||...:.|.|..||..:||:||||||||:||.:.|:||||:|.||
Mouse   452 FFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGD 516

  Fly   786 MAVSSSVGSNIFDVTVGLPIPWLLYGII--YGAPVEVNSVGMVCSITILFMMLVFVVMSIACFRW 848
            ||||:::|||:||:.|||.|||.|..::  ||:.|::||.|:|.|:.:|...:...|:.|...:|
Mouse   517 MAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKW 581

  Fly   849 RMNKGLGFTMFLLYFAFVAVSLMFEYDVIT 878
            |:::.||..:.:||..|:..|:|.|::|.|
Mouse   582 RLDRKLGIYVLVLYAVFLCFSIMIEFNVFT 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	88/143 (62%)
		Na_Ca_ex	721..871	CDD:279963	75/151 (50%)
Slc24a4	NP_742164.2	Na_Ca_ex	<80..606	CDD:332332	219/604 (36%)
		Alpha-1	139..179		31/39 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	358..408		9/53 (17%)
		Alpha-2	495..526		20/30 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820