Protein Alignment Nckx30C and ncx-5

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_505690.2
• Gene: ncx-5 / 191715
• WormBaseID: WBGene00003570
• Length: 656
• Species: Caenorhabditis elegans
• Alignment Length: 634
• Identity: 266/634 - (41%)
• Similarity: 344/634 - (54%)
• Gaps: 110/634 - (17%)

  Fly   302 INDTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKL 366
            |..|.|.||:.     ||.|:|:.:....|.||:||..:||||||||:||||||||||.||.|.|
 Worm    73 IQTTSNANSSQ-----FPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVL 132

  Fly   367 GITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLSL 431
            .|:|||||||||||||||||.|||:.||||:.|:||:|||||||.||||.|:..|.|||:.||.|
 Worm   133 AISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHL 197

  Fly   432 TWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCVKKMITKNK 496
            ||||||||.|||::||.:|:.||.|..|.|.|||::|::||.|..|||:|..:|...|:.:.: |
 Worm   198 TWWPLFRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFNGFLELKTKQFLFR-K 261

  Fly   497 VTRVRSTDQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGS 561
            |                             .:.|..|.||..    .:.||.|..|....|..|.
 Worm   262 V-----------------------------GIGSEIAPETIV----DAAAGCTPRSPHSLGAQGP 293

  Fly   562 TQT------GAKFRHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQRGG------ 614
            .::      |.:.|..:.||:|.          ||..|...:.:|.....:..||...|
 Worm   294 RRSFPMIHGGQEVRKSIAQLVIG----------DEDDTSSSSSSSSSERSNKIKPVSNGVPEIRQ 348

  Fly   615 --------------ATTSAANHVKINLKETTLAD-------------RPNGNIDTTLDSPSLSGR 652
                          |..:..|.:|..:......|             |.|||..|.|........
 Worm   349 NGRTIMVKPANDPDAKFNNQNSIKTVITPIDFGDDHTIVINNNNNGKRKNGNNGTYLTPVEAINP 413

  Fly   653 RPSWIEQRVKIQTR----------KFSIKAPEIEDEPEPLSMAWPDTARKRLTYVLVAPLLVPMW 707
            ....:|   ..||.          ..||.:...|   :||.::||:...|:|.|:.:||:..|:.
 Worm   414 SNGHLE---LAQTNGNPVPPIALDNLSIASSTAE---KPLDLSWPEANHKKLIYLFLAPITFPLA 472

  Fly   708 LTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDL 772
            .||||.|.|..::||.:||||:|:||||:|||||||||..|:|..||.|:||||.||||||||||
 Worm   473 YTLPDVRKPSLRKFFAITFIGAILWIAAYSYLMVWWANTIGETFGIPTEIMGLTILAAGTSIPDL 537

  Fly   773 ITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLLY---GIIYGAP---VEVNSVGMVCSITI 831
            ||||||||||.||||||||:|||:|||.||||||||::   |:....|   :.|.|.|:|||:.:
 Worm   538 ITSVIVARKGLGDMAVSSSIGSNLFDVCVGLPIPWLIHFAIGVFKSEPTQNISVTSNGLVCSLGL 602

  Fly   832 LFMMLVFVVMSIACFRWRMNKGLGFTMFLLYFAFVAVSLMFEYDVITCP 880
            ||.||:.::..:|..||:|:|..|..|...|..|..:.::.|...:.||
 Worm   603 LFAMLIVLLTCVAISRWKMDKFFGLLMIFSYCGFCMLCILLETGHLKCP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	99/143 (69%)
		Na_Ca_ex	721..871	CDD:279963	92/155 (59%)
ncx-5	NP_505690.2	Na_Ca_ex	102..244	CDD:279963	97/141 (69%)
		Na_Ca_ex	486..642	CDD:279963	92/155 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158213
Domainoid	1	1.000	199	1.000	Domainoid score	I1784
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2929
OMA	1	1.010	-	-		QHG59101
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103716
Panther	1	1.100	-	-	LDO	PTHR10846
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1587
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.670