Protein Alignment Nckx30C and ncx-6

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_499146.2
• Gene: ncx-6 / 182354
• WormBaseID: WBGene00003571
• Length: 590
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 131/610 - (21%)
• Similarity: 229/610 - (37%)
• Gaps: 195/610 - (31%)

  Fly   333 VILHIIGVIYM---FVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGGSAPELFTSVIGV 394
            :||.|.|||||   |:.::...|:||.||:..|:..|.|::.|||.||||.|..||::|.::..|
 Worm    97 IILIITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASV 161

  Fly   395 FVS---FDDVGIGTIVGSAVFNILFVIGMCAL---FSKTVLSLTWWPLFRDCSFYSISLLVLIYF 453
            ..|   ..|:.:|.:.|:.:|....|:.:...   |...|.|     ..||.:||.::|..|.:.
 Worm   162 LSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEVFS-----SIRDIAFYLVALAFLAFC 221

  Fly   454 FRDNRIFW-----WEALILFTIYIGYVAFMKWNVQVETCVKKMITKN-------KVTRVRSTDQL 506
            |    :::     |..:....:|:.||.         |.:...|..|       ||..|::.|
 Worm   222 F----VYYDHVEIWMPITFLGVYLIYVC---------TVILSQILHNRHKKDEEKVDEVKTVD-- 271

  Fly   507 MPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGSTQTGAKFRHG 571
                  .:|.|                                            ........||
 Worm   272 ------TDSLE--------------------------------------------DDDDIYVSHG 286

  Fly   572 LLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQRGGATTSAANHVKINLKETTLADRP 636
                  |.:  ||          .|.:..::..::|.:|.:..:.....:..|.:||..
 Worm   287 ------HHV--LH----------AHEVMKMEAEIEAVEPLKTWSFRGVVHDFKEHLKPW------ 327

  Fly   637 NGNIDTTLDSPSLSGRRPSWIEQRV---------KIQTRKFSIKAPEIEDEPEPLSMAWPDTARK 692
                      ||:.    .|.|..:         .|....|.:..|..|   :|.|.  |.|
 Worm   328 ----------PSMD----EWDEMNIFQKVIAVLNTIPNFLFKLTIPHSE---QPWSK--PIT--- 370

  Fly   693 RLTYVLVAPLLV----------------PMWL------------TLPDTRTPRGKRFFP-----V 724
             |...|:.|:.:                .:|:            .|..|...:...|:.     .
 Worm   371 -LLQCLICPVFLLFCIQVCSISPFPNSPGLWMYGLILSVLLTAAVLFFTELHKEPPFYKSLISYA 434

  Fly   725 TFIGSIVWIAAFSYLMVWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVS 789
            .|:.||.||...|..:|....:.|..:|:..||:|||.||...||.|||..|.||::|:..||::
 Worm   435 GFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMA 499

  Fly   790 SSVGSNIFDVTVGLPIPWLLYGIIYGAPVEVNSVGMVCSITILFMM------LVFVVMSIACFRW 848
            :::|..:|::.:|..:|:.:      |.::..|:.|:.:.|...:|      |:|.::::...::
 Worm   500 AAIGGQLFNLLIGFGLPFTI------AKIQGKSISMIINPTYRLLMLFLAISLIFTLIAMFAQKY 558

  Fly   849 RMNKGLGFTMFLLY---FAFVAVSL 870
            .:.:...:::..:|   |.|:.:||
 Worm   559 FLRRIHSYSLVFIYISFFVFIGLSL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	47/157 (30%)
		Na_Ca_ex	721..871	CDD:279963	44/164 (27%)
ncx-6	NP_499146.2	Na_Ca_ex	105..249	CDD:279963	45/161 (28%)
		Na_Ca_ex	431..579	CDD:279963	40/153 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810