Protein Alignment Nckx30C and Slc8b1

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_573484.2
• Gene: Slc8b1 / 170756
• MGIID: 2180781
• Length: 585
• Species: Mus musculus
• Alignment Length: 612
• Identity: 145/612 - (23%)
• Similarity: 240/612 - (39%)
• Gaps: 174/612 - (28%)

  Fly   318 FPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGG 382
            ||.:|...      |:.|::..::|:|:.|.:...:||.|:|..|...|.::.:|||.||:|.|.
Mouse    91 FPPNLLPL------AITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGN 149

  Fly   383 SAPELFTSVIGVFVSFDD-----VGIGTIVGSAVFNILFVIGMCALFSKTVLSLTWWPLFRDCSF 442
            .||::|:::    |:|.|     :.||.:.|:.|.....|.|...:....:.:..  |..||.:|
Mouse   150 GAPDIFSAL----VAFSDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASR--PFLRDIAF 208

  Fly   443 YSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCV---KKMITKNKVTRVRSTD 504
            |.:::.:........||....||....:|:.||      |.|..|.   ::..:::.|..:..|.
Mouse   209 YMVAVFLTFTALYLGRITLTWALGYLGLYVFYV------VTVIICTWVYQRQRSRSLVHSISETP 267

  Fly   505 QLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGGTSGSTQTGAKFR 569
            :|:     :.|.|..|                      |||             :.|...|.::|
Mouse   268 ELL-----SESEEDQM----------------------SSN-------------TNSYDYGDEYR 292

  Fly   570 HGLL------QLMIHTIDPLHDGKVDEKATQLHAIA--SLKVLLDATKPQRGGATTSAANHVKIN 626
            ..||      |::|..::||     |.:..:..:|:  .|||                   ||:.
Mouse   293 PLLLGRETTVQILIQALNPL-----DYRKWRTQSISWRVLKV-------------------VKLP 333

  Fly   627 LKETTLADRPNGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPEIEDEPEPLSMAWPDTAR 691
            ::...|...|  .:|.  |....:.:||....|.|                 ..||
Mouse   334 VEFLLLLTVP--VVDP--DKDDRNWKRPLNCLQLV-----------------ISPL--------- 368

  Fly   692 KRLTYVLVAPL------------LVPMWLTLPDTRTPRGKRFFPVTFIGS-------IVWIAAFS 737
                 |||..|            |:|:|..:...    |.....|||..:       :.|:.||.
Mouse   369 -----VLVLTLQSGVYGIYEIGGLLPVWAVVVIV----GTALASVTFFATSNREPPRLHWLFAFL 424

  Fly   738 YLM--VWWANVA-----------GDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVS 789
            ..:  ..|.|.|           |...|:...|:|||.||.|.||.|..:...:||:|:..||.|
Mouse   425 GFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFS 489

  Fly   790 SSVGSNIFDVTVGLPIPWLLYGIIYGAPVEV--NSVGMVCSI--TILFMMLVFVVMSIACFRWRM 850
            :..|..||::.||:.:..||. ||....|||  ...|::..:  :.|.:.|:|.::|:....:::
Mouse   490 ACFGGIIFNILVGVGLGCLLQ-IIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQL 553

  Fly   851 NKGLGFTMFLLYFAFVAVSLMFEYDVI 877
            :|..|..:.|.|..|:.|.|:.|:.||
Mouse   554 SKAYGLCLLLFYICFLVVVLLTEFGVI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	40/148 (27%)
		Na_Ca_ex	721..871	CDD:279963	50/173 (29%)
Slc8b1	NP_573484.2	Na_Ca_ex	103..246	CDD:279963	42/154 (27%)
		Na_Ca_ex	421..574	CDD:279963	46/153 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810