Protein Alignment Nckx30C and slc24a5

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_002936612.2
• Gene: slc24a5 / 100490024
• XenbaseID: XB-GENE-853669
• Length: 546
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 197/595 - (33%)
• Similarity: 295/595 - (49%)
• Gaps: 149/595 - (25%)

  Fly   297 GNQRGINDTHNDN-STTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLD 360
            |.||...|..|:. ...:.:..||:|.||:::.:.|.:|:|.:.::|||:|:||||:.:|:|||:
 Frog    77 GTQRIRRDVENETLCIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLE 141

  Fly   361 VIIEKLGITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFS 425
            ||.|:||::.|||||||||.|.||||..|..:||||:..|:|:.|||||||:|:|.:...|.|.|
 Frog   142 VISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLS 206

  Fly   426 KTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVE----- 485
            .:|..||.|||||||..|:||:..:|....||||:|:|:..|..||..|:..|.:::::.
 Frog   207 LSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMR 271

  Fly   486 ------TCVKKMITKNKVTRVRSTDQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSS 544
                  ||.::.:.
 Frog   272 RFSPCCTCCREAMV--------------------------------------------------- 285

  Fly   545 NAGATGNSSGGGGTSGSTQTGAKFRHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATK 609
                           |:|:              |  :||...|.|          ||.|:...::
 Frog   286 ---------------GNTE--------------H--EPLLGWKED----------SLPVIRRHSR 309

  Fly   610 PQRGGATTSAANHVKINLKETTLADRPNGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPE 674
            ...|           |..:|:          |.:..|.||||.:                    |
 Frog   310 SDSG-----------IFQEES----------DYSQLSISLSGLK--------------------E 333

  Fly   675 IEDEPEPLSMAWPDTARKRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYL 739
            ..:.| |.....|:...||:.:||..|::..::||:||.|..|.|..|.:||:.|.|||:|.:|:
 Frog   334 SSNNP-PSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKRWKNLFILTFLMSAVWISAVTYI 397

  Fly   740 MVWWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLP 804
            :||...|.|:|..||..|||||.|||||||||.:.||:|||:|.||||:|:.||||:||: :.|.
 Frog   398 LVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDM-LCLG 461

  Fly   805 IPWLLYGIIY--GAPVEVNSVGMVCSITILFMMLVFVVMSIACFRWRMNKGLGFTMFLLYFAFVA 867
            :||.:..:..  .|||||||.|:..:...|...::|:.::|....|:::|.||....|:|..||.
 Frog   462 VPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVT 526

  Fly   868 VSLMFEYDVI 877
            :|:::|..:|
 Frog   527 LSILYELGII 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	76/143 (53%)
		Na_Ca_ex	721..871	CDD:279963	70/151 (46%)
slc24a5	XP_002936612.2	2A1904	<95..>274	CDD:273344	83/178 (47%)
		2A1904	<332..536	CDD:273344	87/225 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920