Protein Alignment Nckx30C and slc24a4b

DIOPT Version :9

• Sequence 1: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 587
• Identity: 225/587 - (38%)
• Similarity: 320/587 - (54%)
• Gaps: 94/587 - (16%)

  Fly   303 NDTHNDNSTTTKTPLFPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLG 367
            |.|...|.|......||.|:||..:.::|||:||||..:|||:|||||||::||.||:.|.|||.
Zfish   123 NTTEEKNCTEPAIHEFPDDVFTNAERKSGAVLLHIIAALYMFLALAIVCDDYFVTSLEKICEKLN 187

  Fly   368 ITDDVAGATFMAAGGSAPELFTSVIGVFVSFDDVGIGTIVGSAVFNILFVIGMCALFSKTVLSLT 432
            :::|||||||||||.||||||.||||||::..|||:||||||||||||.:||:|.:|:..|:.||
Zfish   188 LSEDVAGATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLT 252

  Fly   433 WWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWNVQVETCVKKMITKNKV 497
            ||.:|||..||.:|::.||.|..|.:|.|||:|:|..:|..|:..||:|.:::....:...||
Zfish   253 WWAVFRDSFFYILSVVALIVFIYDEKIVWWESLVLVVMYACYILIMKFNSRLQKFFTRKGNKN-- 315

  Fly   498 TRVRSTDQLMPAGNAANSSE-----TSMATQPGGSVTSRAASETRSGPPGSSNAGATGNSSGGGG 557
                     :..||||..||     ||.....|..|  .......:.||
Zfish   316 ---------VANGNAAAGSELEDVKTSKIYSRGSVV--MVDEIINASPP---------------- 353

  Fly   558 TSGSTQTGAKFRHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQRGGATTSAANH 622
                   ..:|....|::|:..    |.|    ..|:|...:.|.:    |:.||   ...:||.
Zfish   354 -------NYRFPEAGLRVMVTN----HFG----PKTRLRMASRLII----TERQR---LVQSANG 396

  Fly   623 VKINLKETTLAD-RP---NGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPEIEDEPEPLS 683
            |     ||.:.| :|   |||:.....:           |::....|..|.:
Zfish   397 V-----ETAVVDGKPDIENGNVPEDKST-----------EEKESELTTPFRL------------- 432

  Fly   684 MAWPDTARKRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMVWWANVAG 748
               ||....|..:::..|||:.::.|:|:....|.:::|.::||.|.||||.|||.|||...:.|
Zfish   433 ---PDGCMNRTKWLISWPLLLILFFTIPNCAKSRWEKYFMLSFILSTVWIAVFSYFMVWMVTIIG 494

  Fly   749 DTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIPWLL--YG 811
            .|..||..:||:||||||||:||.|.|:||||:|.||||||:::|||:||:.|||.:||.|  ..
Zfish   495 YTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWALQTMA 559

  Fly   812 IIYGAPVEVNSVGMVCSITILFMMLVFVVMSIACFRWRMNKGLGFTMFLLYFAFVAVSLMFEYDV 876
            :.||:.|.:||.|::.|:.:|...:...::.|....|:::..||..:.|||..|:..|:|.||:|
Zfish   560 VNYGSVVMINSRGLLYSVVLLLGSVALTILGIHLNHWKLDFKLGVYVLLLYAVFLCFSIMIEYNV 624

  Fly   877 IT 878
            .|
Zfish   625 FT 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nckx30C	NP_652011.3	Na_Ca_ex	336..480	CDD:279963	87/143 (61%)
		Na_Ca_ex	721..871	CDD:279963	71/151 (47%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	198/508 (39%)
		Na_Ca_ex	156..298	CDD:279963	86/141 (61%)
		Na_Ca_ex	467..619	CDD:279963	71/151 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168500at2759
OrthoFinder	1	1.000	-	-		FOG0000196
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820