DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-1 and VMA16

DIOPT Version :9

Sequence 1:	NP_001247111.1	Gene:	VhaPPA1-1 / 45247	FlyBaseID:	FBgn0028662	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_011891.1	Gene:	VMA16 / 856421	SGDID:	S000001068	Length:	213	Species:	Saccharomyces cerevisiae

Alignment Length:	197	Identity:	110/197 - (55%)
Similarity:	139/197 - (70%)	Gaps:	5/197 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SQTFLWLFLAVATILTLYFVMTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGAALGIHTT 74
            |....:|.|.|..:..||.:.||.|..::.|.||..::|||||.|||.|.|.|||||||.||..|
Yeast    18 SHFLYYLVLIVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGLSVVGAAWGIFIT 82

  Fly    75 GTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSMETALSQAAIQNTNWFSG 139
            |:|::|.||:||||.||||||:||||.|||||||.|||.|.:|...:.|...|:     :|.::|
Yeast    83 GSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVATAENMYSK-----SNLYTG 142

  Fly   140 YLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLFGLIVGIYMTS 204
            |.:|.||:.||..||.|||||||.|:.||:||||::|||||||::|||||.:||.|||||:.|..
Yeast   143 YSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILGLLGLIVGLLMAG 207

  Fly   205 KS 206
            |:
Yeast   208 KA 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt1	51..113	CDD:349417	45/61 (74%)
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt2	138..202	CDD:349418	42/63 (67%)
VMA16	NP_011891.1	ATP-synt_Vo_c_ATP6F_rpt1	59..121	CDD:349417	45/61 (74%)
VMA16	NP_011891.1	ATP-synt_Vo_c_ATP6F_rpt2	141..>192	CDD:349418	33/50 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342070
Domainoid	1	1.000	87	1.000	Domainoid score	I1843
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2986
Inparanoid	1	1.050	208	1.000	Inparanoid score	I822
Isobase	1	0.950	-	0	Normalized mean entropy	S432
OMA	1	1.010	-	-		QHG53850
OrthoFinder	1	1.000	-	-		FOG0002690
OrthoInspector	1	1.000	-	-		otm46750
orthoMCL	1	0.900	-	-		OOG6_102000
Panther	1	1.100	-	-	LDO	PTHR10263
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1637
SonicParanoid	1	1.000	-	-		X2155
TreeFam	1	0.960	-	-
	16	15.740