DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-1 and ATP6V0C

DIOPT Version :9

Sequence 1:	NP_001247111.1	Gene:	VhaPPA1-1 / 45247	FlyBaseID:	FBgn0028662	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001185498.1	Gene:	ATP6V0C / 527	HGNCID:	855	Length:	155	Species:	Homo sapiens

Alignment Length:	155	Identity:	50/155 - (32%)
Similarity:	81/155 - (52%)	Gaps:	13/155 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WACLGIGLSVSLSVVGAALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSG 115
            :|.:|...::..|.:|||.|...:||.|....|..|....|::|.|:....:|||||:.|::::.
Human    14 FAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIAN 78

  Fly   116 QLEQFSMETALSQAAIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVK 180
            .|.             .:.:.:..:|..||||:|||..|..|.|:||||.......|....|||.
Human    79 SLN-------------DDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVG 130

  Fly   181 ILIVEIFGSAIGLFGLIVGIYMTSK 205
            ::::.||...:||:||||.:.:::|
Human   131 MILILIFAEVLGLYGLIVALILSTK 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt1	51..113	CDD:349417	21/61 (34%)
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt2	138..202	CDD:349418	27/63 (43%)
ATP6V0C	NP_001185498.1	V_ATP_synt_C	13..118	CDD:130170	37/116 (32%)
ATP6V0C	NP_001185498.1	ATP-synt_Vo_c_ATP6C_rpt2	86..153	CDD:349416	27/66 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810