DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-1 and ATP5MC3

DIOPT Version :9

Sequence 1:	NP_001247111.1	Gene:	VhaPPA1-1 / 45247	FlyBaseID:	FBgn0028662	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001002258.1	Gene:	ATP5MC3 / 518	HGNCID:	843	Length:	142	Species:	Homo sapiens

Alignment Length:	162	Identity:	38/162 - (23%)
Similarity:	56/162 - (34%)	Gaps:	41/162 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 MWACLGIGLSVSLSVVGAALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLS 114
            |:||..:..:.||...|:.:.......|:    :..|........|.:|      .|....:
Human     1 MFACAKLACTPSLIRAGSRVAYRPISASV----LSRPEASRTGEGSTVF------NGAQNGV--- 52

  Fly   115 GQLEQFSMETALSQAAIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSD-------- 171
            .||.|...:|:.....|.....|     .|||.|          .||:.||||.:..
Human    53 SQLIQREFQTSAISRDIDTAAKF-----IGAGAA----------TVGVAGSGAGIGTVFGSLIIG 102

  Fly   172 -AANAALFVKILIVEIFG----SAIGLFGLIV 198
             |.|.:|..::....|.|    .|:|||.|:|
Human   103 YARNPSLKQQLFSYAILGFALSEAMGLFCLMV 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt1	51..113	CDD:349417	10/61 (16%)
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt2	138..202	CDD:349418	21/74 (28%)
ATP5MC3	NP_001002258.1	ATP9	68..142	CDD:164765	23/82 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810