DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-1 and vha-4

DIOPT Version :9

Sequence 1:	NP_001247111.1	Gene:	VhaPPA1-1 / 45247	FlyBaseID:	FBgn0028662	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_495659.1	Gene:	vha-4 / 174272	WormBaseID:	WBGene00006913	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	122/212 - (57%)
Similarity:	159/212 - (75%)	Gaps:	5/212 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AQIRTVVSQTFLWLFLAVATILTLYFVMTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGA 67
            |.::|..:.|.:...:.:.|  .|:::::|:|.|..:||||.|::|:|||.||||.|:||||:||
Worm     5 AILKTTATLTVITTLIILGT--GLFYMLSGQGHRFDIGWFLTSTSPHMWAGLGIGFSLSLSVLGA 67

  Fly    68 ALGIHTTGTSIVGGGVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSME---TALSQA 129
            ..||.|||:||:|||||||||:||||:|:||||||||:|:|.|.|..|:|.:|..|   ......
Worm    68 GWGIFTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIFGIIMAFVFVGKLAEFRREDLPDTEDGM 132

  Fly   130 AIQNTNWFSGYLIFGAGLAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLF 194
            ||...|..|||:|||.||.|||.||.||:||||||||||::||||.||||||||:|||.||||||
Worm   133 AILARNLASGYMIFGGGLTVGLSNLVCGLAVGIVGSGAAIADAANPALFVKILIIEIFASAIGLF 197

  Fly   195 GLIVGIYMTSKSKMGDK 211
            |:|:||..|:|:..|:|
Worm   198 GMIIGIVQTNKASFGNK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt1	51..113	CDD:349417	45/61 (74%)
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt2	138..202	CDD:349418	50/63 (79%)
vha-4	NP_495659.1	ATP-synt_C	54..114	CDD:278563	44/59 (75%)
vha-4	NP_495659.1	ATP-synt_C	145..204	CDD:278563	46/58 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157607
Domainoid	1	1.000	95	1.000	Domainoid score	I4652
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2986
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2123
Isobase	1	0.950	-	0	Normalized mean entropy	S432
OMA	1	1.010	-	-		QHG53850
OrthoDB	1	1.010	-	-		D1408246at2759
OrthoFinder	1	1.000	-	-		FOG0002690
OrthoInspector	1	1.000	-	-		otm14810
orthoMCL	1	0.900	-	-		OOG6_102000
Panther	1	1.100	-	-	LDO	PTHR10263
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1637
SonicParanoid	1	1.000	-	-		X2155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790