DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-1 and Atp6v0b

DIOPT Version :9

Sequence 1:	NP_001247111.1	Gene:	VhaPPA1-1 / 45247	FlyBaseID:	FBgn0028662	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_291095.1	Gene:	Atp6v0b / 114143	MGIID:	1890510	Length:	205	Species:	Mus musculus

Alignment Length:	194	Identity:	123/194 - (63%)
Similarity:	150/194 - (77%)	Gaps:	3/194 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FLAVATILTLYFVMTGKGERVSVGWFLASSNPYMWACLGIGLSVSLSVVGAALGIHTTGTSIVGG 81
            |.|...::.:.:.:...|.|..|.|||..::|:||:.|||||::||||||||.||:.||:||:||
Mouse    15 FWACMVVVGICYTIFDLGFRFDVAWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGG 79

  Fly    82 GVKAPRIKTKNLISVIFCEAVAIYGLITAIVLSGQLEQFSMETALSQAAIQNTNWFSGYLIFGAG 146
            ||||||||||||:|:||||||||||:|.|||:|...|.||   |....||.:.|:.:||.:||||
Mouse    80 GVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFS---ATEPKAIGHRNYHAGYSMFGAG 141

  Fly   147 LAVGLVNLFCGIAVGIVGSGAALSDAANAALFVKILIVEIFGSAIGLFGLIVGIYMTSKSKMGD 210
            |.|||.|||||:.||||||||||:||.|.:|||||||||||||||||||:||.|..||:.||||
Mouse   142 LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt1	51..113	CDD:349417	48/61 (79%)
VhaPPA1-1	NP_001247111.1	ATP-synt_Vo_c_ATP6F_rpt2	138..202	CDD:349418	50/63 (79%)
Atp6v0b	NP_291095.1	ATP-synt_Vo_c_ATP6F_rpt1	49..111	CDD:349417	48/61 (79%)
Atp6v0b	NP_291095.1	ATP-synt_Vo_c_ATP6F_rpt2	133..197	CDD:349418	50/63 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833677
Domainoid	1	1.000	100	1.000	Domainoid score	I7023
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2986
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3340
Isobase	1	0.950	-	0	Normalized mean entropy	S432
OMA	1	1.010	-	-		QHG53850
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002690
OrthoInspector	1	1.000	-	-		oto94028
orthoMCL	1	0.900	-	-		OOG6_102000
Panther	1	1.100	-	-	LDO	PTHR10263
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1637
SonicParanoid	1	1.000	-	-		X2155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740