DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CYTB and CYTB

DIOPT Version :9

Sequence 1:	YP_003024038.1	Gene:	CYTB / 4519	HGNCID:	7427	Length:	380	Species:	Homo sapiens
Sequence 2:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	377	Identity:	232/377 - (61%)
Similarity:	302/377 - (80%)	Gaps:	8/377 - (2%)

- Green bases have known domain annotations that are detailed below.

Human     3 PMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIA 67
            |:|.::||.|:.|::.:|||.|.|||:|||||||||.|||:||.|||||||||:.|.:.||.|:.
  Fly     4 PLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVN 68

Human    68 HITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSETWNIGIILLLATMATAFMGYV 132
            ||.|||||||::|.|||||||.||||::||:|||:||||:.::.||.||:|:|...|.|||||||
  Fly    69 HICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPTWLIGVIILFLVMGTAFMGYV 133

Human   133 LPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAALATLHL 197
            |||||||||||||||||||||||:|.|||||:|||::||:.|||||||||||||||:.|:..:||
  Fly   134 LPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHL 198

Human   198 LFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGDPDNYTLANPL 262
            ||||:||||||:|:.|:.|||.||||:|.||.:|.::.:..|::|.|.||:|||||||:..||||
  Fly   199 LFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPANPL 263

Human   263 NTPPHIKPEWYFLFAYTILRSVPNKLGGVLALLLSILILAMIPILHMSKQQSMMFRPLSQSLYWL 327
            .||.||:|||||||||.||||:|||||||:||:|||.||.::|..::||.:.:.|.|::|.::|.
  Fly   264 VTPAHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILMILPFYNLSKFRGIQFYPINQVMFWS 328

Human   328 LAADLLILTWIGGQPVSYPFTIIGQVASVLYFTTILILMPTISLIENKMLKW 379
            :...:::|||||.:||..|:.:|||:.:|:||...|: .|.|:       ||
  Fly   329 MLVTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLV-NPLIT-------KW 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CYTB	YP_003024038.1	CYTB	1..379	CDD:177162	230/375 (61%)
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	224/354 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160471
Domainoid	1	1.000	311	1.000	Domainoid score	I1317
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1268
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60605
OrthoDB	1	1.010	-	-		D1125966at2759
OrthoFinder	1	1.000	-	-		FOG0004155
OrthoInspector	1	1.000	-	-		oto90764
orthoMCL	1	0.900	-	-		OOG6_102198
Panther	1	1.100	-	-	LDO	PTHR19271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R280
SonicParanoid	1	1.000	-	-		X1779
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.940