Protein Alignment COX1 and COX1

DIOPT Version :10

• Sequence 1: YP_003024028.1
• Gene: COX1 / 4512
• HGNCID: 7419
• Length: 513
• Species: Homo sapiens
• Sequence 2: NP_006961.1
• Gene: COX1 / 2565700
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 310/511 - (60%)
• Similarity: 395/511 - (77%)
• Gaps: 7/511 - (1%)

Human     6 WLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLGNDHIYNVIVTAHAFVMIFFMV 70
            ||.|:|||||||||.:||.|:|::||:.|||||.||.:||..|.|..:||.::||||.:||||||
 Worm    14 WLESSNHKDIGTLYFIFGLWSGMVGTSFSLLIRLELAKPGFFLSNGQLYNSVITAHAILMIFFMV 78

Human    71 MPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGN 135
            ||.|||||||||:|||:|||||:|||:||:||||||.|:||:|.:..|:.|.||.|||||||: .
 Worm    79 MPTMIGGFGNWLLPLMLGAPDMSFPRLNNLSFWLLPTSMLLILDACFVDMGCGTSWTVYPPLS-T 142

Human   136 YSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLP 200
            ..|||:||||.|||||.||:|||||.|||:.|..|::..:::.....||||:|.:|..||:||||
 Worm   143 MGHPGSSVDLAIFSLHAAGLSSILGGINFMCTTKNLRSSSISLEHMTLFVWTVFVTVFLLVLSLP 207

Human   201 VLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKK 265
            |||..||||||||||||:||||:.||:|::|||||||||||||||||||.||::|....|.:|||
 Worm   208 VLAGAITMLLTDRNLNTSFFDPSTGGNPLIYQHLFWFFGHPEVYILILPAFGIVSQSTLYLTGKK 272

Human   266 EPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGS 330
            |.||.:|||:|::|||.:|.:||||||:|||||:|:||||::|||:||:|||||||||||||.|.
 Worm   273 EVFGALGMVYAILSIGLIGCVVWAHHMYTVGMDLDSRAYFSAATMVIAVPTGVKVFSWLATLFGM 337

Human   331 NMKWSAAVLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIH 395
            .|.::..:||.||||||||:|||||:||:||||||:||||||||:|||||||:||||.|..|...
 Worm   338 KMVFNPLLLWVLGFIFLFTLGGLTGVVLSNSSLDIILHDTYYVVSHFHYVLSLGAVFGIFTGVTL 402

Human   396 WFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNILSSVGSFI 460
            |:...:||.||:......|.::||||||||||.||.||.|.||:|.||||.|:.|||::|.||.|
 Worm   403 WWSFITGYVLDKLMMSAVFILLFIGVNLTFFPLHFAGLHGFPRKYLDYPDVYSVWNIIASYGSII 467

Human   461 SLTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYGCPPPY---HTFEEPVYMKS 513
            |...:.|.|:::.|:|.|.|.|:.....:.:.|:   |...|   |:::..:|..:
 Worm   468 STAGLFLFIYVLLESFFSYRLVISDYYSNSSPEY---CMSNYVFGHSYQSEIYFST 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COX1	YP_003024028.1	COX1	5..507	CDD:177210	309/503 (61%)
COX1	NP_006961.1	COX1	8..515	CDD:177148	309/503 (61%)