DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nsun2 and AT4G40000

DIOPT Version :9

Sequence 1:	NP_652007.1	Gene:	Nsun2 / 45064	FlyBaseID:	FBgn0026079	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_195710.3	Gene:	AT4G40000 / 830161	AraportID:	AT4G40000	Length:	783	Species:	Arabidopsis thaliana

Alignment Length:	818	Identity:	263/818 - (32%)
Similarity:	388/818 - (47%)	Gaps:	160/818 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRNQKQNFFAARKRQKRENGPKRTDRQAQPYE-EIKRD----------NAFFIKYYQLQKICAT 54
            |||.::.. .:..||.:.||  ...|...:|.: |...|          |..|.:||:.|:|...
plant     1 MGRGRRHR-GSTSKRNQIEN--SNDDNVRKPLKSEASFDSNNLQKPICSNLHFEEYYKEQRIVKA 62

  Fly    55 DEEWTQFLASIRDNLPTTFRVTG---FKDEAKALLSIIETQLFTEYVRAV-AELHQKAPEDVERP 115
             :||..|:..:|..||..|||..   |.||       |..:|..:::.:: ||..:....:..:|
plant    63 -QEWDSFMEFLRKPLPAAFRVYSNGQFCDE-------IRLKLENDFMISLQAEAIESGELEAIKP 119

  Fly   116 LCLPWYPNGLAYQLHLTRKDIRRSEPLYRLHNFLIVETTAGGISRQEAVSMIPPIVLDVRPTDKV 180
              |||||..||:..:.:||:||:::.|.|.|.||.:||.||.::|||:|||:||:.|||.|...|
plant   120 --LPWYPKNLAWHSNFSRKEIRKNQTLERFHEFLKLETEAGNMTRQESVSMVPPLFLDVHPDHFV 182

  Fly   181 LDMCAAPGSKTAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQAKRLNSPCLLVTNHDSS 245
            |||||||||||.||:|.:|.:.|...:|.|.|:|||||..|..:|:||.||..:..|:|||::..
plant   183 LDMCAAPGSKTFQLLEIIHESSEPGSLPNGMVVANDVDYKRSNLLIHQTKRTCTTNLMVTNNEGQ 247

  Fly   246 VFPNLVT---------TKPDGSKAILKFDKILCDVPCSGDGTLRKNPDIWLKWNLAQAYNLHGIQ 301
            .||:..|         |.|.....:| ||::||||||||||||||.||||.:||......||.:|
plant   248 HFPSCNTKRTLSVASETNPHPIDQLL-FDRVLCDVPCSGDGTLRKAPDIWRRWNSGSGNGLHSLQ 311

  Fly   302 YRIVRRGAEMLEVGGRLVYSTCSLNPIENEAVLQRIIKDADGALELVDAGHLVPGLKYKPGMTDW 366
            ..:..||..:|:||||:||||||:||||:|||:..|::....::||||....:|.|..:||:|.|
plant   312 VVLAMRGLSLLKVGGRMVYSTCSMNPIEDEAVVAEILRRCGCSVELVDVSDKLPELIRRPGLTKW 376

  Fly   367 KLATKEVDQIFTRFEEVPESLHTIIRPGMFPL------------------------PADEMAKIG 407
            |:..:  ...:..:::||:|....:...|||.                        .|:|:..:.
plant   377 KVHDR--GGWYRSYKDVPKSQRDGVLRSMFPSGKSDKDSSGGKNSYEEMASISSDESAEEVCDLP 439

  Fly   408 LEKCLRVLPHLQDSGGFFVAVLEK-------------RRQLSFEKN--------------DVVEL 445
            ||.|:|:|||.|::||||:|||.|             :|.||...|              |.| :
plant   440 LELCMRILPHDQNTGGFFIAVLHKVSPLPDFQEKVTQKRNLSTRNNINSSEKSSSYEAVSDTV-V 503

  Fly   446 VKLNETAKQPAAEPQVDADGKPIEEKSVPWGP-----QRKKRRLHGYKEDPY----------VFF 495
            .|..|..::...|..|..:|....|....|..     .:|...:.|.:|.|.          |.|
plant   504 TKPEEGTEEIVLEATVSENGFEPPEMESTWNEGIVELAQKLDDIEGKREVPSMQGKWKGLYPVVF 568

  Fly   496 GENDPDYQAIKEFYQL-DESLSQRCLLTRCVTEKK--------KNIYYCSEPIRDLVLNN---EN 548
            ..:......||.||.: |||..   |....||...        |.|||.|:.:::::..|   ..
plant   569 LRDQTGINGIKTFYGIKDESFP---LYGHLVTRNSDISSHGNVKRIYYVSKAVKNVLELNFAVGK 630

  Fly   549 NIKIINTGVKTFVR-----CENRHTVHPFRLAQEGLQTSNAFMGASRRIQVEREDLVMMLNCTDP 608
            .:||.:.|:|.|.:     ||  .....||:..|||.....:| ..:.:.....|...:|.
plant   631 PLKISSVGLKMFEKQSAKECE--ANCCSFRITSEGLPVILPYM-TKQILYATMADFKNLLQ---- 688

  Fly   609 TQPPSTHE-------LKKETQERCKELGVGSCILKYVD------QRF----TLYTVG-WRGTSSL 655
                  |:       :..:..|:..||.:|||::..||      ::|    :...:| |:|.:||
plant   689 ------HKSIKFLDFIHPQIGEKAAELALGSCVMVLVDDSQLGSEQFKVNSSTIAIGCWKGKASL 747

  Fly   656 RAYVQKDETIHILRLLGADLSKFETNKYEDARVAAAAA 693
            ...|...:...:::.| :|.|| |..|.|:....|..|
plant   748 TVMVTTVDCHQLIQRL-SDRSK-EKEKAENCFKTAETA 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nsun2	NP_652007.1	RsmB	13..433	CDD:223222	185/480 (39%)
AT4G40000	NP_195710.3	RsmB	50..465	CDD:223222	176/427 (41%)
AT4G40000	NP_195710.3	AdoMet_MTases	171..>350	CDD:302624	92/179 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	189	1.000	Domainoid score	I958
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9817
Inparanoid	1	1.050	347	1.000	Inparanoid score	I625
OMA	1	1.010	-	-		QHG54313
OrthoDB	1	1.010	-	-		D911098at2759
OrthoFinder	1	1.000	-	-		FOG0002888
OrthoInspector	1	1.000	-	-		otm2894
orthoMCL	1	0.900	-	-		OOG6_101428
Panther	1	1.100	-	-	O	PTHR22808
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2247
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840