Protein Alignment Nsun2 and NSUN3

DIOPT Version :10

• Sequence 1: NP_652007.1
• Gene: Nsun2 / 45064
• FlyBaseID: FBgn0026079
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_071355.1
• Gene: NSUN3 / 63899
• HGNCID: 26208
• Length: 340
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 95/389 - (24%)
• Similarity: 146/389 - (37%)
• Gaps: 108/389 - (27%)

  Fly    82 AKALLSIIETQLFTEYVRAVAELHQKAPEDVERPLCLPW----------YPNGLAYQLHLTRKDI 136
            ||.:..::......:|.:.:.:......|.:..|.|  |          ||..|...|||.....
Human    14 AKQICKVVLDHFEKQYSKELGDAWNTVREILTSPSC--WQYAVLLNRFNYPFELEKDLHLKGYHT 76

  Fly   137 --RRSEPLYRLHNFLIVETTAGGISRQ-------------EAVSMIPPIVLDVRPTDKVLDMCAA 186
              :.|.|.|.......:..|.|.|..:             .|.|::|.:.|::|..:||||:|||
Human    77 LSQGSLPNYPKSVKCYLSRTPGRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAA 141

  Fly   187 PGSKTAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQAKRLNSPCLLVTNHDSSVFPNLV 251
            ||.|:..|::.         ..||::..|:.|:.|...| .|......|..|:         |::
Human   142 PGGKSIALLQC---------ACPGYLHCNEYDSLRLRWL-RQTLESFIPQPLI---------NVI 187

  Fly   252 -TTKPDGSK----AILKFDKILCDVPCSGDGTLRKNPDIWL--------KWNLAQAYNLHGIQYR 303
             .::.||.|    ....|||:|.|.|||.|.:       ||        ...::|..||..:|..
Human   188 KVSELDGRKMGDAQPEMFDKVLVDAPCSNDRS-------WLFSSDSQKASCRISQRRNLPLLQIE 245

  Fly   304 IVRRGAEMLEVGGRLVYSTCSLNPIENEAVLQRIIKDADGALELVDAGHLVPGLKYKPGMTDWKL 368
            ::|...:.|..||.||||||:|:..||:.|:..|:.         ..|:::|        .|.|.
Human   246 LLRSAIKALRPGGILVYSTCTLSKAENQDVISEILN---------SHGNIMP--------MDIKG 293

  Fly   369 ATKEVDQIFTRFEEVPESLHTIIRPGMFPLPADEMAKIGLEKCLRVLPHLQDS-GGFFVAVLEK 431
            ..:.....||                        .|..|.|..|.|:|....: |..:||.|:|
Human   294 IARTCSHDFT------------------------FAPTGQECGLLVIPDKGKAWGPMYVAKLKK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsun2	NP_652007.1	RsmB	<55..433	CDD:439914	95/389 (24%)
NSUN3	NP_071355.1	RsmB	<118..333	CDD:439914	75/281 (27%)