Protein Alignment Nsun2 and NSUN5

DIOPT Version :9

• Sequence 1: NP_652007.1
• Gene: Nsun2 / 45064
• FlyBaseID: FBgn0026079
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_001161819.1
• Gene: NSUN5 / 55695
• HGNCID: 16385
• Length: 470
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 120/504 - (23%)
• Similarity: 175/504 - (34%)
• Gaps: 157/504 - (31%)

  Fly     1 MGRNQKQNFFAARKRQKRENGPKRTD------RQAQPYEEIKRDNAFFIKYYQLQKICATDEEWT 59
            :||:|.: ..|...|.|...|..|.:      .:..|..::.|    |::...| |.|:
Human    95 LGRHQAR-LKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPR----FVRVNTL-KTCS------ 147

  Fly    60 QFLASIRDNLPTTFRVTGFKDEAKALLSIIETQLFTEYVRAVAELHQKAPEDVERPLCLPWYPNG 124
                   |::...|:..||..:.:|  |.::.      :||:...|.         |..|..|..
Human   148 -------DDVVDYFKRQGFSYQGRA--SSLDD------LRALKGKHF---------LLDPLMPEL 188

  Fly   125 LAY----QLHLTRKDIRRSEPLYRLHNFLIVETTAGGISRQEAVSMIPPIVLDVRPTDKVLDMCA 185
            |.:    .||        ..||||          ||.:..|:..|.:|.::||..|...|:|.||
Human   189 LVFPAQTDLH--------EHPLYR----------AGHLILQDRASCLPAMLLDPPPGSHVIDACA 235

  Fly   186 APGSKTAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQAKRLNSPCLLVTNHDSSVFPNL 250
            |||:||:.|...|.        ..|.:.|.|:|..|...:.....|....|..:...|      .
Human   236 APGNKTSHLAALLK--------NQGKIFAFDLDAKRLASMATLLARAGVSCCELAEED------F 286

  Fly   251 VTTKPDGSKAILKFDKILCDVPCSGDGTLRKNPDIWLKW------NLAQAYNLHGIQYRIVRRGA 309
            :...|...: ..:...||.|..|||.|.    |...|:.      :..:.:.|.|.|.|.:....
Human   287 LAVSPSDPR-YHEVHYILLDPSCSGSGM----PSRQLEEPGAGTPSPVRLHALAGFQQRALCHAL 346

  Fly   310 EMLEVGGRLVYSTCSLNPIENEAVLQRIIKDADGALELVDAGHLVPGLKYKPGMTDWK---LATK 371
            ....: .|||||||||...|||.|::..::...||..|.            |.:..|.   |:|
Human   347 TFPSL-QRLVYSTCSLCQEENEDVVRDALQQNPGAFRLA------------PALPAWPHRGLST- 397

  Fly   372 EVDQIFTRFEEVPESLHTIIRPGMFPLPADEMAKIGLEKCLRVLPHLQDSGGFFVAVLEKRRQLS 436
                                    ||         |.|.|||..|....|.||||||:|:
Human   398 ------------------------FP---------GAEHCLRASPETTLSSGFFVAVIER----- 424

  Fly   437 FEKNDVVELVKLNETAKQPAAEPQVDADGKPIEEKSVPWGPQRKKRRLH 485
                  ||:..|  |.:..:.........|..||.:     :.:.|.||
Human   425 ------VEVPSL--TGQSISTRTHTQPSPKEKEETA-----KSRSRCLH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsun2	NP_652007.1	RsmB	13..433	CDD:223222	106/438 (24%)
NSUN5	NP_001161819.1	RsmB	95..425	CDD:223222	110/460 (24%)
		AdoMet_MTases	219..420	CDD:302624	68/266 (26%)
		S-adenosyl-L-methionine binding	234..240		5/5 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810