Protein Alignment Nsun2 and NSUN6

DIOPT Version :10

• Sequence 1: NP_652007.1
• Gene: Nsun2 / 45064
• FlyBaseID: FBgn0026079
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_047280733.1
• Gene: NSUN6 / 221078
• HGNCID: 23529
• Length: 473
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 89/360 - (24%)
• Similarity: 146/360 - (40%)
• Gaps: 115/360 - (31%)

  Fly   123 NGLAYQLHLTRKD----------------IRRSEPLYR-------LHNFLIVETTAGGISRQEAV 164
            ||::   .|:||:                ||.:||:|.       |..:|.:         |...
Human   174 NGIS---ELSRKEIFSGLPELKYVIRGMGIRMTEPVYLSPSFDSVLPRYLFL---------QNLP 226

  Fly   165 SMIPPIVLDVRPTDKVLDMCAAPGSKTAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQA 229
            |.:...||:.:|.:|:||:|||||.||..:...:|        ..|.|:|.|       .:.::.
Human   227 SALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMH--------DQGEVIALD-------KIFNKV 276

  Fly   230 KRLNSPCLLVTNHDSSVFPNLVTTKPDGSKAIL----------------KFDKILCDVPCSGDGT 278
            :::....||:..:....|..      ||:||:.                .||:||.|.||||.|
Human   277 EKIKQNALLLGLNSIRAFCF------DGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG- 334

  Fly   279 LRKNPDIWLKWNLAQAYNLHGIQYRIVRRGAEMLEVGGRLVYSTCSLNPIEN-EAVLQRIIKDAD 342
              :.|::...|::.:..:...:|.::.....::|:..|.||||||::...|| |.|...:.|
Human   335 --QRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTK--- 394

  Fly   343 GALELVDAGHLVPGLKYKP--------GMTDWKLATKEVDQIFTRFEEVPESLHTIIRPGMFPLP 399
                       .|.|:.:|        ||....|:.:::.|: .||:           |...|||
Human   395 -----------FPCLQLQPQEPQIGGEGMRGAGLSCEQLKQL-QRFD-----------PSAVPLP 436

  Fly   400 ---ADEMAKIGLEKCLRVLPHLQDSGGFFVAVLEK 431
               .|.:.:...|..||:..  :||.|||:|...|
Human   437 DTDMDSLREARREDMLRLAN--KDSIGFFIAKFVK 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsun2	NP_652007.1	RsmB	<55..433	CDD:439914	89/360 (25%)
NSUN6	XP_047280733.1	PUA_NSun6-like	113..206	CDD:409292	8/34 (24%)
		RsmB	<199..469	CDD:439914	83/330 (25%)