Protein Alignment Nsun2 and nsun-2

DIOPT Version :10

• Sequence 1: NP_652007.1
• Gene: Nsun2 / 45064
• FlyBaseID: FBgn0026079
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_490830.3
• Gene: nsun-2 / 171697
• WormBaseID: WBGene00021686
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 750
• Identity: 249/750 - (33%)
• Similarity: 403/750 - (53%)
• Gaps: 88/750 - (11%)

  Fly     1 MGRNQKQNFFAARKRQKRENGPKRTDRQA---QPYEEIKRDNAFFIKYYQLQKICATDEEWTQFL 62
            |..:.::.|.:..|..:......|.||.|   |.|..::::|..:.:||:.|.:... |::.:|.
 Worm     1 MVHSSRRKFKSKNKGHEPRENVWRDDRDAPGNQGYRMVEKENEKYWQYYKEQNVFPL-EQFDEFR 64

  Fly    63 ASIRDNLPTTFRVTGFKDEAKALLSIIETQLFTEYVRAVAELHQKAPEDVERPLCLPWYPNGLAY 127
            |:::.:||.:||..|...:.:.|:..:|.:.|.:.:.|       ....|..|..||||..  ||
 Worm    65 AALQRDLPVSFRFQGCHKDREQLIHEMENRFFGKIMEA-------GDTAVCVPKSLPWYKE--AY 120

  Fly   128 QLHLTRKDIRRSEPLYRLHNFLIVETTAGGISRQEAVSMIPPIVLDVRPTDK--VLDMCAAPGSK 190
            |..::|..:|....|.:|||||:.|...|.:|||||||||||::|  .||.:  |||:|||||||
 Worm   121 QTPMSRTAVRSHPILAQLHNFLVTEAELGNLSRQEAVSMIPPLLL--APTSEHFVLDLCAAPGSK 183

  Fly   191 TAQLIEALHAAPEEHKIPPGFVLANDVDNNRCYMLVHQA-KRLNSPCLLVTNHDSSVFPNLVTTK 254
            |.||:|.:|   |..:.|.|.|:|||||..|||||:|.. ||..:....||..|::.||::
 Worm   184 TTQLLEMIH---ENEENPKGMVIANDVDMKRCYMLIHHTLKRFRTAACAVTCEDAARFPHI---- 241

  Fly   255 PDGSKAILKFDKILCDVPCSGDGTLRKNPDIWLKWNLAQAYNLHGIQYRIVRRGAEMLEVGGRLV 319
            .|....:::||::|.||.|||||||||||:||.||.......||.:|..|.|:||:.|:||||:|
 Worm   242 SDSDGGLIQFDRVLADVICSGDGTLRKNPEIWKKWTPQDGLGLHRMQIAIARKGAQQLKVGGRMV 306

  Fly   320 YSTCSLNPIENEAVLQRIIKDADGALELVDAGHLVPGLKYKPGMTDWKLATKEVDQIFTRFEEV- 383
            |||||:||||:|||:.::::|:.|:|:|||...|:|.||.:.|:..||:..::: :::...|::
 Worm   307 YSTCSMNPIEDEAVVAQLLRDSKGSLKLVDTSSLLPELKRETGVVQWKVFDRDM-KLYKSLEDIS 370

  Fly   384 PESLHTIIRPGMFPLPADEMAKIGLEKCLRVLPHLQDSGGFFVAVLEKRRQLSFEKNDVVELVKL 448
            .|.:..:|...:||....|..::.|...:|:.||.||:||||||::|                |:
 Worm   371 EEKMKKVIVSSLFPPTEQEAKEMNLHFTMRITPHAQDTGGFFVALIE----------------KV 419

  Fly   449 NETAKQPAAEPQVDADGKPIEEKSVPWGPQRKKRRLHGYKEDPYVFFGENDPDYQAIKEFYQLDE 513
            :||:..|:|..                ||..||:::  :|::|:.|...:|..:..|:..|.:||
 Worm   420 SETSFDPSAAN----------------GPAWKKKKM--FKDEPFTFLKLDDERWNDIRNHYGVDE 466

  Fly   514 SLSQRCLLTRCVTEKKKN---IYYCSEPIRDLVLNNENNIKIINTGVKTFVRCENRHTVHPFRLA 575
            |...:.|.:|.:.....|   ::|.::.:::.|..|.:.:.|.|.|:|.|.|.|.:.....|||:
 Worm   467 SFLYQNLFSRRLESNDANSRQLFYANDAVKNFVKENMSKVSIQNAGMKMFSRTEGKVENTRFRLS 531

  Fly   576 QEGLQTSNAFMGASRRIQVEREDLVMMLNCTDPTQPPSTHELKKETQERCKELGVGSCILKYVDQ 640
            |||::....|| ..:::::..||::.||...:...|....|.|.:.:::     ....::.|.|.
 Worm   532 QEGIRYLFKFM-QKQKVKIGTEDMLFMLKSDENLVPLEKLECKGDVRKQ-----QNGTVVVYCDD 590

  Fly   641 RFTLYTVGWRGTSSLRAYVQKDETIHILRLLGADLSKFE---TNKYEDARVAAAAAADAEVGKSA 702
            ...:.|  |.|..::..|:.|:|.:|:||::|.|.::.|   .:|.::.......||.|...::|
 Worm   591 DEPVCT--WVGYHTIAPYISKEERLHLLRMMGVDCAEIELLMKSKRKEKAAQDREAAWARKEEAA 653

  Fly   703 EAEADSSGDGDATESTFSGSGAIDVTVAAETTGTP 737
            :|...||...||.||             |||...|
 Worm   654 KAAEPSSSSTDAPES-------------AETLEIP 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nsun2	NP_652007.1	RsmB	<55..433	CDD:439914	160/381 (42%)
nsun-2	NP_490830.3	RsmB	<46..420	CDD:439914	164/409 (40%)