DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and SERPIN1

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001320925.1	Gene:	SERPIN1 / 841182	AraportID:	AT1G47710	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	383	Identity:	105/383 - (27%)
Similarity:	172/383 - (44%)	Gaps:	49/383 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESYHNLLHSYIKS 102
            :.|..|:.|||.||.||.:.|.:...|:.|.|..::...|..|   |.|.|     |...|.|.|
plant    49 ITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFS---STDQL-----NSFSSEIVS 105

  Fly   103 KTV----------LEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDF-SRETEAVEQINRWVK 156
            ..:          |.:||..:..::|:....|:::.:..:.:.....|| |:..|.:.::|.|.:
plant   106 AVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEVNSWAE 170

  Fly   157 QQTENKIERVVE--SLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFADN 219
            ::|...|..|:.  |.:..|.:...||:|||..|...|::..|::.||.|.:...:..|.|.:..
plant   171 KETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNKVTAPFMTSKK 235

  Fly   220 WYYYADY--------PELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQ 276
            ..|.:.|        |.|..:      :....:|:|.||:..:||..|..|:.... ..|::...
plant   236 KQYVSAYDGFKVLGLPYLQGQ------DKRQFSMYFYLPDANNGLSDLLDKIVSTP-GFLDNHIP 293

  Fly   277 WQSVSV---YLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTR--ITKVQHKTFI 336
            .:.|.|   .:|||||.|..|....|..:|:::.||.....:.:.:...:|..  ::.:.||..|
plant   294 RRQVKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACI 358

  Fly   337 DVNEIGCEAAGASYAAGV----PMSLPLDPKTFVADHPFAFIIRDK--HAVYFTGHIV 388
            :|||.|.|||.||  |||    .:.:..|...|||||||..::.:.  ..|.|.|.:|
plant   359 EVNEEGTEAAAAS--AGVIKLRGLLMEEDEIDFVADHPFLLVVTENITGVVLFIGQVV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	104/380 (27%)
SERPIN1	NP_001320925.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970