DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and zgc:173729

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001103200.1	Gene:	zgc:173729 / 798311	ZFINID:	ZDB-GENE-071004-64	Length:	439	Species:	Danio rerio

Alignment Length:	431	Identity:	131/431 - (30%)
Similarity:	201/431 - (46%)	Gaps:	82/431 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTL----------------H 78
            |:..||:.::......||..|||||..||.:...||:|.||.::.|.|                .
Zfish    11 FSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNPPKPGGATPTPAQ 75

  Fly    79 ASAK---------------------------------------ESKDGLAESYHNLLHSYIK--S 102
            |:.|                                       ::::.:..|::..:....|  :
Zfish    76 ATQKPQITCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFNKFMSELNKPGA 140

  Fly   103 KTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVE-QINRWVKQQTENKIERV 166
            ..||.:||::|..|.......|...|:.|:.:.:|.:||..::||.. .||:||::.|:.||:.:
Zfish   141 PYVLSLANRLYGEQTYQFLEKFLSDAKTYYAAGLEKVDFKNKSEASRVNINKWVEKNTQEKIKDL 205

  Fly   167 VES--LEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWYYYADYPEL 229
            :.|  ::..|.:.||||||||..|.:.|..|.|||.:|.|:::::..|..|.....:..|..||:
Zfish   206 LPSGAIDAMTRLVLVNAIYFKGNWEKKFTKEATRDGQFKLNKNQTKPVKMMHQKARFSLASIPEM 270

  Fly   230 DAKAIELFFENINLTMWFILPNQ----RSGLQALEQKLKGVDFNLLEDRWQW--------QSVSV 282
            :::.:||.:...||:|..|||:|    .:|||.||:.|      ..|...:|        |.|.|
Zfish   271 NSQVLELPYAGKNLSMLIILPDQIEDATTGLQKLEKAL------TYEKLMEWTKPSMMCQQEVQV 329

  Fly   283 YLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAG 347
            .|||||.|...|::..|..||:..:| |....:.....|.....::||.||.|::|||.|.|||.
Zfish   330 SLPKFKTEQTYDMKSLLVSMGMEDVF-DPQKVNLTGMSSSNDLVLSKVIHKAFVEVNEEGTEAAA 393

  Fly   348 ASYAAGVPMSLPLD-PKTFVADHPFAFIIRDK--HAVYFTG 385
            |:.......|:||. ||||.|||||.|.||..  :|:.|.|
Zfish   394 ATGVIATLTSMPLSPPKTFTADHPFIFFIRHNPTNAILFYG 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	131/431 (30%)
zgc:173729	NP_001103200.1	SERPIN	4..439	CDD:294093	131/431 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.730