DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and zgc:174259

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_021331992.1	Gene:	zgc:174259 / 791587	ZFINID:	ZDB-GENE-080213-10	Length:	410	Species:	Danio rerio

Alignment Length:	396	Identity:	116/396 - (29%)
Similarity:	201/396 - (50%)	Gaps:	41/396 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISAPEGLGNTIKDRNLFATELFQTL--ATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKT 76
            |||.  |.:.|...|.||..|::.|  :.|.|.:|:..||.|:.:||.....||.|.|..:|...
Zfish    29 ISAK--LPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSG 91

  Fly    77 L-HASAKESKDGLAESYHNLLHSYIKSKT--VLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEP 138
            : ::||..|.:.:.:.:|:||.. |.::|  .:::...:|........|.|.|..::::.|:...
Zfish    92 IGYSSAIFSTEEMHQLFHSLLED-IGNRTGVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDGFT 155

  Fly   139 LDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFW 203
            :|||.: |.|:|||::|:::|..||.:.|:.|:.||.:.|:..||||.:|.:|||.:.|.:..|.
Zfish   156 VDFSVK-ETVDQINKYVEEKTHGKINQAVDDLDADTFMVLLTYIYFKGKWDKPFNPKTTSESTFH 219

  Fly   204 LSESRSIQVPTMFA-DNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVD 267
            :.:..::.|..|.. :....|.| .||..|.:.|.: |.:.:|:..:|:...|.:.::.....|.
Zfish   220 IDDKTTVPVQMMHQYERLKVYYD-AELSTKVLCLDY-NDSFSMFLAVPDVHMGRKTIKDLEMTVS 282

  Fly   268 FNLLEDRWQWQSVS-----VYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRI 327
            ...:| :|: :|||     :|:||...:....|:..|..||::.||||.|||:.:.::.   ..:
Zfish   283 RQHVE-KWR-RSVSERKVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKADFTGVSEEK---IYV 342

  Fly   328 TKVQHKTFIDVNEIGCEAAGA--------SYAAGVPMSLPLDPKTFVADHPFAFIIRDK--HAVY 382
            :||.||..:|::|.|..||..        ||:       |:...:|  |.||...|.|:  ..:.
Zfish   343 SKVLHKATLDIDEKGTTAAAVTTVHLRFMSYS-------PMSDLSF--DRPFMIFITDQTNDNIL 398

  Fly   383 FTGHIV 388
            |.|.:|
Zfish   399 FVGKVV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	110/379 (29%)
zgc:174259	XP_021331992.1	alpha-1-antitrypsin_like	39..403	CDD:239011	110/381 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010