Protein Alignment Spn43Aa and Serpina3a

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001161177.1
• Gene: Serpina3a / 74069
• MGIID: 1921319
• Length: 422
• Species: Mus musculus
• Alignment Length: 408
• Identity: 114/408 - (27%)
• Similarity: 196/408 - (48%)
• Gaps: 45/408 - (11%)

  Fly     5 LSIILLGV------WISAPEGLG---NTIKDRNL---------------FATELFQTLATDRQDE 45
            |.:::.|:      |.:|...||   ...|||:.               ||..|::.||.....:
Mouse     7 LGLLMAGICPAITYWATADGQLGRHTEVQKDRDHEIQLDSVTLASINTDFAFSLYKKLALKNPHK 71

  Fly    46 NVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDG-LAESYHNLLHSYIKSKTVLEI- 108
            |::.||:||..||.|...||:..|..|:.:.|..:..|:.:. :.:::.:||...|:.:..::|
Mouse    72 NIVFSPLSISAALALMSLGAKDNTLEEILEGLKFNLTETPEADIHQNFGHLLQMLIQPENQVQIN 136

  Fly   109 -ANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVKQQTENKIERVVESLEP 172
             .|.::..::|.:.:.|:|.|:..:.:|....||....||.:.||.:|::||:.||:.:|..|..
Mouse   137 AGNALFIDKHLQILTEFKEKARALYKAEAFTADFQLPREATKLINDYVRKQTQGKIKELVSDLHR 201

  Fly   173 DTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFAD--NWYYYADYPELDAKAIE 235
            :|::||||.:.|:..|...|:.|||....|.|...|::.||.|..:  ...|:.| .|:.:..:|
Mouse   202 NTSMALVNFLNFQGFWNVTFDPEDTFLGNFTLDRKRTVNVPMMKTEELTTNYFRD-EEMQSTVME 265

  Fly   236 LFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQWQSV------SVYLPKFKFEFDTD 294
            |.:.. |.:..||||:| ..:|.:|..|:.....    :|: :|:      .:.||||....|.:
Mouse   266 LNYIG-NASFLFILPDQ-GRIQHVEDSLQPQSLR----KWR-KSLRPRMLDELSLPKFSLSQDYN 323

  Fly   295 LRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLP 359
            |...|.::||..:||..||.|.|.....|  |::::.|:..:||.|...||...:.|.....|..
Mouse   324 LNDILPELGIKEVFSTQADLSGITGAKNI--RVSQMIHQAALDVTETHTEADVITIARYNFQSAK 386

  Fly   360 LDPKTFVADHPFAFIIRD 377
            :..|....|..|.::|.|
Mouse   387 IKAKIVKVDREFLYLILD 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	106/377 (28%)
Serpina3a	NP_001161177.1	serpinA3_A1AC	39..419	CDD:381019	105/376 (28%)