DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpine3

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	403	Identity:	89/403 - (22%)
Similarity:	177/403 - (43%)	Gaps:	51/403 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GVWISAPEGLGNTIKDRNLFATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQK 75
            |:|:...|           ||..|:|:.|.:....|.:|||.|:.|:|.:..:.|.|.|..:|.:
  Rat    27 GLWLLKTE-----------FALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAE 80

  Fly    76 TLHASAKESKDGLAESYHNL---LHSYIKSKTV-LEIANKVYTRQNLTVSSHFREVAQKYFDSEV 136
            .|..:.::.:  :.|..|.:   ||:  .|:.: :|:|..::.:...::|..|.|...::.:|.:
  Rat    81 ALGYTVQDPR--VREFLHTVYITLHN--SSQGIGMELACTLFMQTGTSLSPCFVEQVSRWANSSL 141

  Fly   137 EPLDFSRETEAVEQINRWVKQQTENKIERVVESLEP-----------DTNVALVNAIYFKARWAR 190
            |..|||.......:.::...:.:..:        .|           .|.:::|:.:.|::.|.:
  Rat   142 ELADFSEPNTTTMEASKGTTRPSTGE--------GPGSPLWGRAGALSTQLSIVSTMTFQSSWQQ 198

  Fly   191 PFNDEDTRDREFWLSESRSIQVPTMFADNWYYYADYPEL---DAKAIELFFENINLTMWFILPNQ 252
            .|:....:...|..:....:|||.|.......|..:.:.   ....:||.:.....::..:||..
  Rat   199 RFSSVALQPLPFTCAHGLVLQVPAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQD 263

  Fly   253 R-SGLQALEQKLKGVDFNLLEDRWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSD-AADFS 315
            : :.|..:|..|.....:|...|.:...:.|:||:|:.:...||:..|...||:.:|.. .|:..
  Rat   264 KGTPLDHIEPHLTARVIHLWTTRLKRARMDVFLPRFRIQNQFDLKSILRSWGITDLFDPLKANLK 328

  Fly   316 NIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDKH- 379
            .|  ....|..:::|.||..::::|.|.::..|:  |.:.:.....| .|.||.||.|::|:.:
  Rat   329 GI--SGRDGFYVSEVTHKAKMELSEEGTKSCAAT--AVLLLRRSRTP-AFKADRPFIFLLREHNT 388

  Fly   380 -AVYFT-GHIVKF 390
             ||..| |.:..|
  Rat   389 VAVRITHGKVANF 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	85/381 (22%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	88/400 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110