Protein Alignment Spn43Aa and Serpinb1a

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_079705.2
• Gene: Serpinb1a / 66222
• MGIID: 1913472
• Length: 379
• Species: Mus musculus
• Alignment Length: 396
• Identity: 132/396 - (33%)
• Similarity: 195/396 - (49%)
• Gaps: 66/396 - (16%)

  Fly    29 LFATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESYH 93
            |||.||||||.......|:..||.||..||.:...||:|.|||:|.||.|..:.|.
Mouse    10 LFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHFDSVED--------- 65

  Fly    94 NLLHSYIKS----------KTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETE-A 147
              :||..:|          ...|::||::|..:.......:....||.:.:::.|:||...:| |
Mouse    66 --IHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDA 128

  Fly   148 VEQINRWVKQQTENKIER-----VVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSES 207
            .::||:|||.|||.||..     ||:|:   |.:.||||||||..|...|..|||.|..|.||:.
Mouse   129 RKEINQWVKGQTEGKIPELLSVGVVDSM---TKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKK 190

  Fly   208 RSIQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFILP----NQRSGLQALEQKLKGVDF 268
            .:..|..|:....:.:....:|..|.:|:.::...|:|..:||    ::.:||:.:|:::
Mouse   191 DTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQI----- 250

  Fly   269 NLLEDRWQWQ--------SVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDA-ADFSNIFQDSPIG 324
             .||...:|.        .|.|.||:||.|....|...|.::|:..:||.: ||.|.:     .|
Mouse   251 -TLEKLLEWTKRENLEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGM-----SG 309

  Fly   325 TR---ITKVQHKTFIDVNEIGCEAAGASYAAGVP---MSLPLDPKTFVADHPFAFIIRDKHA--V 381
            :|   |:|:.||:|::|||.|.|||.|:  .|:.   |.||  .:.|..||||.|.||....  |
Mouse   310 SRDLFISKIVHKSFVEVNEEGTEAAAAT--GGIATFCMLLP--EEEFTVDHPFIFFIRHNPTSNV 370

  Fly   382 YFTGHI 387
            .|.|.:
Mouse   371 LFLGRV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	132/396 (33%)
Serpinb1a	NP_079705.2	serpinB1_LEI	1..379	CDD:381028	132/396 (33%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	351..379		11/26 (42%)