Protein Alignment Spn43Aa and SERPINE3

DIOPT Version :9

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 97/380 - (25%)
• Similarity: 170/380 - (44%)
• Gaps: 35/380 - (9%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASA--KESKDGLAESY 92
            ||..|:|::|..|.:.|.:|||..:.|.|.:..:||||.|..:|...|..:.  |..||.|...|
Human    33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVY 97

  Fly    93 HNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVKQ 157
            ..|..|  ...|.:|:|..::.:....:|..|.|....:.:|.:||.|.|.......|.:....:
Human    98 ATLPTS--SQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASR 160

  Fly   158 QTEN----------KIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQV 212
            :|..          ..|:|..:.   ..:.||:.:.|:..|.:.|:..||:...|..:....:||
Human   161 ETAGGGPSEGPGGWPWEQVSAAF---AQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQV 222

  Fly   213 PTMFAD---NWYYYADYPELDAKAIELFFENINLTMWFILPNQR-SGLQALEQKLKGVDFNLLED 273
            |.|...   |:..:.|........:||.:....::::.:||..: :.|..:|..|.....:|...
Human   223 PMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTT 287

  Fly   274 RWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSD-AADFSNIF-QDSPIGTRITKVQHKTFI 336
            ..:...:.|:||:|:.:...:|:..|:..|::.:|.. .|:...|. ||   |..:::..||..|
Human   288 SLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQD---GFYVSEAIHKAKI 349

  Fly   337 DVNEIGCEAAGASYAAGVPMS-LPLDPKTFVADHPFAFIIRDKHAVYFTGHIVKF 390
            :|.|.|.:|:||:....:..| :|:    |.||.||.:.:|:.:    ||..|.|
Human   350 EVLEEGTKASGATALLLLKRSRIPI----FKADRPFIYFLREPN----TGITVFF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	95/375 (25%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	97/380 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		4/30 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020