DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	403	Identity:	112/403 - (27%)
Similarity:	191/403 - (47%)	Gaps:	55/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISAPEGLGNTIKDRNLFATELFQTL--ATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKT 76
            |||.  |.:.|...|.||..|::.:  :.|.|.:|:..||.|:.:||.....||.|.|.   |:.
Zfish    29 ISAK--LPSLINMNNDFAFHLYKRVIESPDYQSKNIFFSPFSVSIALSELSLGAGGDTK---QQL 88

  Fly    77 LHASAKESKDGLAESYHNLLHSYI-----KSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEV 136
            |......|.....|..|.|.||.:     ::...:::...:|........|.|.|..::::.|:.
Zfish    89 LSGIGYNSTTFSTEEMHQLFHSLLEDIGNRTGVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDG 153

  Fly   137 EPLDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDRE 201
            ..:|| |..|.|:|||.:.|::|:.|..:.|:.||.||.:.|:..||||.:|.:||..|.||:..
Zfish   154 FTVDF-RVKETVDQINNYAKKKTQGKFNQAVDDLEEDTLMFLLTYIYFKGKWDKPFKPEKTREST 217

  Fly   202 FWLSESRSIQVPTM--------FADNWYYYADYPELDAKAIELFFENINLTMWFILPN---QRSG 255
            |.:.:..::.|..|        |.|        .||..|.:.|.::: :.:|:..:|:   :...
Zfish   218 FHIDDKTTVPVQMMHQYERLKVFYD--------AELSTKVLCLDYKD-SFSMFLAVPDDKMEHKN 273

  Fly   256 LQALEQKLKGVDFNLLEDRWQ----WQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSN 316
            ::.||..:....|    ::|:    .::|.:|:||...:....|:..|..||::.||||.|:|:.
Zfish   274 IKDLEMTVSRQHF----EKWRRSAFKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKANFTG 334

  Fly   317 IFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSL----PLDPKTFVADHPFAFIIRD 377
            :.::...   ::||.||..:|::|.|..||..:   ||.|.:    ||....|  :.||...|.|
Zfish   335 VSEEKIF---VSKVLHKATLDIDEQGTTAAAVT---GVSMRVRLHNPLSILKF--NRPFMVFITD 391

  Fly   378 K--HAVYFTGHIV 388
            :  ..:.|.|.:|
Zfish   392 QTNDNILFFGKVV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	106/386 (27%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	106/388 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020