DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and serpina7

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_021331940.1	Gene:	serpina7 / 564060	ZFINID:	ZDB-GENE-041010-47	Length:	425	Species:	Danio rerio

Alignment Length:	394	Identity:	116/394 - (29%)
Similarity:	198/394 - (50%)	Gaps:	37/394 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISAPEGLGNTIKDRNLFATELFQTL--ATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKT 76
            |||.  |.:.|...|.||..|::.|  :.|.|.:|:..||.|:.:||.....||.|.|.   |:.
Zfish    44 ISAK--LPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTK---QQL 103

  Fly    77 LHASAKESKDGLAESYHNLLHSYI-----KSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEV 136
            |......|.....|..|.|.||.:     :::..:::...:|........|.|.|..::::.|:.
Zfish   104 LSGIGYNSAIFSTEEMHQLFHSLLEEIGNRTEVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDG 168

  Fly   137 EPLDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDRE 201
            ..:|||.: |.|:|||::|:::|..||.:.|::||.||.:.|:..||||.:|.:||..|.|.:..
Zfish   169 FTVDFSVK-ETVDQINKYVEEKTHGKISQAVDNLEKDTLMFLLTYIYFKGKWDKPFKPETTSEST 232

  Fly   202 FWLSESRSIQVPTMFA-DNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKG 265
            |::.:..::.|..|.. ::...|.|. ||..|.:.|.: |.:.:|...:|:    :...::.:|.
Zfish   233 FYIDDKTTVPVQMMHQYEHLKVYYDV-ELFTKVLCLDY-NDSFSMILAVPD----VYMKQKTMKD 291

  Fly   266 VDFNLLE---DRWQWQSVS-----VYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSP 322
            ::..:..   ::|: :|||     :|:||...:....|:..|..||::.||||.|||:.:.:::.
Zfish   292 LEMTVSRQHIEKWR-RSVSERKVDIYVPKLSLKTSYSLKDILKGMGMTDMFSDKADFTGVSEENI 355

  Fly   323 IGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSL-PLDPKTFVADHPFAFIIRDK--HAVYFT 384
            .   ::||.||..:|::|.|..||..:.....|.|. ||....|  ||||...|.|:  ..:.|.
Zfish   356 F---VSKVLHKATLDIDEQGTTAAAVTGVEIRPTSYDPLSDLKF--DHPFMIFITDQTNDNILFV 415

  Fly   385 GHIV 388
            |.:|
Zfish   416 GKVV 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	110/377 (29%)
serpina7	XP_021331940.1	alpha-1-antitrypsin_like	54..418	CDD:239011	110/379 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010