Protein Alignment Spn43Aa and SERPINI2

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_006208.1
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 106/372 - (28%)
• Similarity: 187/372 - (50%)
• Gaps: 25/372 - (6%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESYHN 94
            ||.:|:|.::...:| |:|.||:.|.|.|.:...||:|:...::::||    |:.:....|.:.
Human    29 FAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTL----KQQETSAGEEFF- 87

  Fly    95 LLHSYI------KSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINR 153
            :|.|:.      |.:....:||.:|.::..||...:....:::|.|.::.:||.......|.|:.
Human    88 VLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMIST 152

  Fly   154 WVKQQTENKIERVV--ESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMF 216
            ||:::|:.||:.:.  |...|.|.:.||||||||..|.:.|..|||:...|......::::|.|.
Human   153 WVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMK 217

  Fly   217 A--DNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQWQS 279
            |  ...|.|.....|:.:.:||.::....::..|||.:...::.:|:.:............|.:.
Human   218 ALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEE 282

  Fly   280 VSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCE 344
            |.:.||:||.|...|.:..|:.:.|:.:||...|.|.|...|.:  .:::|..|.|.::||.|.|
Human   283 VEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSEV--YVSQVTQKVFFEINEDGSE 345

  Fly   345 AAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDKH----AVYFTGHI 387
            || .|....:|:.:.|....|:|:|||.||:  ||    ::.|.|.:
Human   346 AA-TSTGIHIPVIMSLAQSQFIANHPFLFIM--KHNPTESILFMGRV 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	106/372 (28%)
SERPINI2	NP_006208.1	serpinI2_pancpin	23..392	CDD:381042	106/372 (28%)