Protein Alignment Spn43Aa and SERPINB13

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 113/395 - (28%)
• Similarity: 193/395 - (48%)
• Gaps: 55/395 - (13%)

  Fly    33 ELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGL--------- 88
            :||:.| ....|.|:..|||.|..|:|:...|..|.||::|::..| |.||:|...
Human    14 DLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFH-SEKETKSSRIKAEEKEVV 76

  Fly    89 -----------AESYHNLLHSYIK--SKTV----LEIANKVYTRQNLTVSSHFREVAQKYFDSEV 136
                       .|:.|.....::.  ||..    |.|.|:::..:.......:.:..:||:.:.:
Human    77 RIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHASL 141

  Fly   137 EPLDF-SRETEAVEQINRWVKQQTENKIERVVE--SLEPDTNVALVNAIYFKARWARPFNDEDTR 198
            ||:|| :...|:.::||.||:.:|..||:.:..  |:...|.:.|||.:|||.:|.|.|..|:|:
Human   142 EPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTK 206

  Fly   199 DREFWLSESRSIQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKL 263
            :.:||:::|.|..|..|...:.:.:....:|.||.:.:.::|.:|:|:.:|||...||:.:..|:
Human   207 EEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKI 271

  Fly   264 KGVDFNLLEDRWQWQS--------VSVYLPKFKFEFDTDLRPTLHKMGISAMFSD-AADFSNIFQ 319
            ..      |...:|.|        |:::||:|:.|...||...|..||:...||: .||:|.:..
Human   272 SP------EKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSS 330

  Fly   320 DSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDP--KTFVADHPFAFIIR--DKHA 380
            .|  |....|..|.:|:.|.|.|.|||.|:   |:..::...|  :....:|||.|.||  :.::
Human   331 GS--GLYAQKFLHSSFVAVTEEGTEAAAAT---GIGFTVTSAPGHENVHCNHPFLFFIRHNESNS 390

  Fly   381 VYFTG 385
            :.|.|
Human   391 ILFFG 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	113/395 (29%)
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	113/395 (29%)