Protein Alignment Spn43Aa and SERPINI1

DIOPT Version :9

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 113/374 - (30%)
• Similarity: 202/374 - (54%)
• Gaps: 24/374 - (6%)

  Fly    31 ATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTL-HASAKESKD-GLAESYH 93
            :..::..|....:|||::.||:||.||:|:...||:|.|..|::.:: :.|.|..:: ...:.:.
Human    30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFS 94

  Fly    94 NLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVKQQ 158
            |::.:. :|:.|::|||.::.:....|:..|.::.:|||::.|..:|||:.......||:||:..
Human    95 NMVTAK-ESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENN 158

  Fly   159 TENKIERVVESLEPD--TNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWY 221
            |.|.::.:|...:.|  |.:||:||:|||..|...|..|:||...|...:...:|:|.|:....:
Human   159 TNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEF 223

  Fly   222 YYADYPELDAKA------IELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRW----Q 276
            ||.::.:...:|      :|:.:|...::|..:|..|...|..||..:|.   .|:|: |    :
Human   224 YYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKA---QLVEE-WANSVK 284

  Fly   277 WQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEI 341
            .|.|.||||:|..|.:.||:..|..:||:.:|...|:.:.:..:..|  .::|..||:|::|||.
Human   285 KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEI--FLSKAIHKSFLEVNEE 347

  Fly   342 GCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDKH--AVYFTGHIV 388
            |.|||..|....:.....|.|:..| ||||.|:||::.  .:.|.|.::
Human   348 GSEAAAVSGMIAISRMAVLYPQVIV-DHPFFFLIRNRRTGTILFMGRVM 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	113/371 (30%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	113/374 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830