Protein Alignment Spn43Aa and SERPINB6

DIOPT Version :9

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 122/370 - (32%)
• Similarity: 199/370 - (53%)
• Gaps: 23/370 - (6%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESYHN 94
            ||..|.:||..| ..:||..||:|:..||.:.|.||:|.|||::.:.|..:.......:.:.:.:
Human    89 FALNLLKTLGKD-NSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQS 152

  Fly    95 LLHSYIKSKT--VLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQ----INR 153
            ||....|:.|  :|.:||:::..::....|.||:..||::.:|:|.|||   ..|||:    ||.
Human   153 LLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDF---ISAVEKSRKHINT 214

  Fly   154 WVKQQTENKIERVVE--SLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMF 216
            ||.::||.||..::.  |::|.|.:.||||:||:..|...|:.|:|.:|.|.:|::....|..||
Human   215 WVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMF 279

  Fly   217 ADNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKL---KGVDFNLLEDRWQWQ 278
            ..:.:......|:..:.:.|.:....|.|..:||::.:.|:.:|::|   |.|::..| |....:
Human   280 KQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRL-DMMDEE 343

  Fly   279 SVSVYLPKFKFEFDTDLRPTLHKMGISAMFS-DAADFSNIFQDSPIGTRITKVQHKTFIDVNEIG 342
            .|.|.||:||.|...|:...|..:|::..|. ..||||.:.|..   ..::||.||:|::|||.|
Human   344 EVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTD---LSLSKVVHKSFVEVNEEG 405

  Fly   343 CEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDK--HAVYFTG 385
            .|||.|:.|..:.......|: |.|||||.|.|:..  :.:.|.|
Human   406 TEAAAATAAIMMMRCARFVPR-FCADHPFLFFIQHSKTNGILFCG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	122/370 (33%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	122/370 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730