Protein Alignment Spn43Aa and SERPINB5

DIOPT Version :9

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 106/377 - (28%)
• Similarity: 193/377 - (51%)
• Gaps: 41/377 - (10%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLH-ASAKESKDGL--AES 91
            ||.:||:.|.......||:.||:.:..:|.||..||:|.||.|:.:.|| .:.|:...|.  ..|
Human    11 FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTS 75

  Fly    92 YHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVE-QINRWV 155
            ..|.|.|:..    |::..::|..::|.:|:.|....::.:..|:|.:||..:.|..: |||..:
Human    76 DVNKLSSFYS----LKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSI 136

  Fly   156 KQQTENKIERVV--ESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFAD 218
            |..|:...|.::  .|:...|.:.:|||.||..:|.:.|::.:|::..|.::::.:..|..|..:
Human   137 KDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNME 201

  Fly   219 NWYYYADYPELDAKAIELFFENINLTMWFILP----NQRSGLQALEQKLKGVDFNLLEDRWQWQS 279
            ..:...:...::.|.|||.|:|.:|:|:.:||    ::.:||:.:|::|..      |...||.:
Human   202 ATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNS------ESLSQWTN 260

  Fly   280 --------VSVYLPKFKFEFDTDLRPTLHKMGISAMFS-DAADFSNIFQDSPIGTRITKVQHKTF 335
                    |.:.:||||.|...|.:..|..:|:..:|| |.:|||.:.:..  |..::.|.||..
Human   261 PSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETK--GVALSNVIHKVC 323

  Fly   336 IDVNEIGCEAAGASYAAGVPMSLPLDPKTFV-ADHPFAFIIR---DKHAVYF 383
            :::.|.|.:      :..||.:..|..|..: |||||.:|||   .::.::|
Human   324 LEITEDGGD------SIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFF 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	106/377 (28%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	106/377 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930