Protein Alignment Spn43Aa and SERPINB5

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 106/377 - (28%)
• Similarity: 193/377 - (51%)
• Gaps: 41/377 - (10%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLH-ASAKESKDGL--AES 91
            ||.:||:.|.......||:.||:.:..:|.||..||:|.||.|:.:.|| .:.|:...|.  ..|
Human    11 FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTS 75

  Fly    92 YHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVE-QINRWV 155
            ..|.|.|:..    |::..::|..::|.:|:.|....::.:..|:|.:||..:.|..: |||..:
Human    76 DVNKLSSFYS----LKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSI 136

  Fly   156 KQQTENKIERVV--ESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFAD 218
            |..|:...|.::  .|:...|.:.:|||.||..:|.:.|::.:|::..|.::::.:..|..|..:
Human   137 KDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNME 201

  Fly   219 NWYYYADYPELDAKAIELFFENINLTMWFILP----NQRSGLQALEQKLKGVDFNLLEDRWQWQS 279
            ..:...:...::.|.|||.|:|.:|:|:.:||    ::.:||:.:|::|..      |...||.:
Human   202 ATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNS------ESLSQWTN 260

  Fly   280 --------VSVYLPKFKFEFDTDLRPTLHKMGISAMFS-DAADFSNIFQDSPIGTRITKVQHKTF 335
                    |.:.:||||.|...|.:..|..:|:..:|| |.:|||.:.:..  |..::.|.||..
Human   261 PSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETK--GVALSNVIHKVC 323

  Fly   336 IDVNEIGCEAAGASYAAGVPMSLPLDPKTFV-ADHPFAFIIR---DKHAVYF 383
            :::.|.|.:      :..||.:..|..|..: |||||.:|||   .::.::|
Human   324 LEITEDGGD------SIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFF 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	106/377 (28%)
SERPINB5	NP_002630.2	serpinB5_maspin	1..375	CDD:381013	106/377 (28%)