Protein Alignment Spn43Aa and SERPINA1

DIOPT Version :9

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 111/367 - (30%)
• Similarity: 195/367 - (53%)
• Gaps: 18/367 - (4%)

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDG-LAESYH 93
            ||..|::.||......|:..|||||..|..:...|.:..|..|:.:.|:.:..|..:. :.|.:.
Human    57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQ 121

  Fly    94 NLLHSYIKSKTVLEI--ANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVK 156
            .||.:..:..:.|::  .|.::..:.|.:...|.|..:|.:.||...::|....||.:|||.:|:
Human   122 ELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186

  Fly   157 QQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWY 221
            :.|:.||..:|:.|:.||..||||.|:||.:|.|||..:||.:.:|.:.:..:::||.|.....:
Human   187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMF 251

  Fly   222 YYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKG---VDFNLLEDRWQWQSVSVY 283
            ......:|.:..:.:.:.. |.|..|.||:: ..||.||.:|..   ..|...|||   :|.|::
Human   252 NIQHCKKLSSWVLLMKYLG-NATAIFFLPDE-GKLQHLENELTHDIITKFLENEDR---RSASLH 311

  Fly   284 LPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGA 348
            |||.......||:..|.::||:.:||:.||.|.:.:::|:  :::|..||..:.::|.|.|||||
Human   312 LPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPL--KLSKAVHKAVLTIDEKGTEAAGA 374

  Fly   349 SYAAGVPMSLPLDPKTFVADHPFAFIIRDKH--AVYFTGHIV 388
            .:...:|||:|.:.|   .:.||.|::.:::  :..|.|.:|
Human   375 MFLEAIPMSIPPEVK---FNKPFVFLMIEQNTKSPLFMGKVV 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	110/364 (30%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	110/364 (30%)
		RCL	368..392		11/26 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010