Protein Alignment Spn43Aa and SERPINC1

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 105/435 - (24%)
• Similarity: 188/435 - (43%)
• Gaps: 72/435 - (16%)

  Fly    17 PEGLGNTI----KDRNLFATELFQTLATDRQD-ENVIISPVSIQLALGLAYYGAEGRTAAELQKT 76
            ||.....:    |..:.|||..:|.||..:.| :|:.:||:||..|..:...||...|..:|.:.
Human    73 PEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEV 137

  Fly    77 LHASAKESKDGLAESYHNLLHSYI------------KSKTVLEIANKVYTRQNLTVSSHFREVAQ 129
            .      ..|.::|...:.:|.:.            ||..::. ||:::..::||.:..::::::
Human   138 F------KFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVS-ANRLFGDKSLTFNETYQDISE 195

  Fly   130 KYFDSEVEPLDFSRETE-AVEQINRWVKQQTENKIERVV--ESLEPDTNVALVNAIYFK------ 185
            ..:.::::||||....| :...||:||..:||.:|..|:  |::...|.:.|||.||||
Human   196 LVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMAL 260

  Fly   186 -----------------------------------ARWARPFNDEDTRDREFWLSESRSIQVPTM 215
                                               ..|...|:.|:||...|:.::..|.....|
Human   261 ERPQGLPLALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMM 325

  Fly   216 FADNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQWQSV 280
            :.:..:.|....| ..:.:||.|:..::||..|||.....|..:|::|.........|..:...:
Human   326 YQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMML 389

  Fly   281 SVYLPKFKFEFDTDLRPTLHKMGISAMFS-DAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCE 344
            .|::|:|:.|....|:..|..||:..:|| :.:....|..:......::...||.|::|||.|.|
Human   390 VVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSE 454

  Fly   345 AAGASYAAGVPMSLPLDPKTFVADHPFAFIIRD--KHAVYFTGHI 387
            ||.::.......||..:..||.|:.||...||:  .:.:.|.|.:
Human   455 AAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRV 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	102/421 (24%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	105/435 (24%)