DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and serpind1

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_878300.1	Gene:	serpind1 / 359841	ZFINID:	ZDB-GENE-030711-2	Length:	507	Species:	Danio rerio

Alignment Length:	382	Identity:	103/382 - (26%)
Similarity:	192/382 - (50%)	Gaps:	29/382 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NTIKDRNLFATELFQTLATD-RQDENVIISPVSIQLALGLAYYGAEGRTAAELQKT------LHA 79
            |.:..|  |...|::.|... .|.:|::::||.|.:|:|:...|....|..:|.:|      ::|
Zfish   135 NVVNAR--FGFRLYRKLRNRLNQTDNILLAPVGISIAMGMMGLGVGPNTQEQLFQTVGFAEFVNA 197

  Fly    80 SAKESKDGLAESYHNLLHSYIKSK--TVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFS 142
            |.......:.:.:..|.|...:..  ..|...|.:|.::|:.:...||..|:.|:.:|.:.:||:
Zfish   198 SNHYDNSTVHKLFRKLTHRLFRRNFGYTLRSVNDLYVKRNVQIQDSFRADAKTYYFAEPQSVDFA 262

  Fly   143 RETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSES 207
             :...:.:.|:.:::.|:..|:..::|::|:..|.|:|.:|||..|.:.|..|.|..|:|.::|.
Zfish   263 -DPAFLVKANQRIQKITKGLIKEPLKSVDPNMAVMLLNYLYFKGTWEQKFPKELTHHRQFRVNEK 326

  Fly   208 RSIQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLE 272
            :.::|..|.....|..|...||:...::|.:.. |::|...:|.:.||:::|||::...    |.
Zfish   327 KQVRVLMMQNKGSYLAAADHELNCDILQLPYAG-NISMLIAVPQKLSGMRSLEQEISPT----LV 386

  Fly   273 DRWQWQSVS----VYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHK 333
            ::|.....:    |..|:||.|.:.||...|.:||::.:|::..|||.:..:..|   |...:|:
Zfish   387 NKWLSNMTNRTREVVFPRFKLEQNYDLIEHLKEMGMTDIFTEKGDFSPMTSEKVI---INWFKHQ 448

  Fly   334 TFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDKH--AVYFTGHIV 388
            ..|.|||.|.|||..::...:|:|   ....|:.|.||.|:|.:..  .|.|.|.:|
Zfish   449 GSITVNEEGTEAAAMTHIGFMPLS---TQTRFIVDRPFLFLIYEHRTGCVVFMGRVV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	100/373 (27%)
serpind1	NP_878300.1	HCII	61..505	CDD:239002	103/382 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020