DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpina1f

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001101524.1	Gene:	Serpina1f / 314406	RGDID:	1307899	Length:	412	Species:	Rattus norvegicus

Alignment Length:	364	Identity:	79/364 - (21%)
Similarity:	171/364 - (46%)	Gaps:	19/364 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESYHNLLHS 98
            ||:.:|....:.|::.||:.:..|:.:...||:|..:..:.:.|    :.:|.||.|:..:....
  Rat    55 LFKEMAQLSVNGNILFSPIRVIAAISMLSLGAKGNESKRILEIL----RLNKTGLPEAEIHKCFR 115

  Fly    99 YI-------KSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVK 156
            |:       :..:.|:..:.|:..|:||....|.|..:..:.|::..::|:....|..|||.::.
  Rat   116 YLLRAIHQPEQLSPLKSGSGVFIHQDLTPVDKFVEGVKNLYHSDIVSINFTDCRRAKTQINNYMM 180

  Fly   157 QQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWY 221
            .::..:|:.:|::||.||.:|:||.|.:.|:....|.....:.:::.|.:..:|:||.:...:..
  Rat   181 TKSNKEIKNIVKNLENDTYMAVVNYIIWNAKINSDFGCRSVKQKDYHLEQGMTIKVPMIHIVDLN 245

  Fly   222 YYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQWQSVSVYLPK 286
            :.....:|.:..:.......|.|.:||:|: ...:|.:||:|....|..:..:...:.|::..|:
  Rat   246 HLFRVEDLSSTVLVFTLLASNFTTYFIIPD-IGQMQKVEQRLTYPHFRRMRRQSNLRMVNLETPE 309

  Fly   287 FKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYA 351
            .......|:...::.:||:.:|::.|:.|.:..|:.  .:..|:..|..:.:::.|.: .|.|..
  Rat   310 LSLSETHDVESMMNLLGITYVFNNDANSSAVMNDTL--QKSFKMVSKVKLTIDDKGSK-PGRSTC 371

  Fly   352 AGVPMSLPLDPKTFVADHPFAFIIRD--KHAVYFTGHIV 388
            .....|:.:....|  :.||...|:|  .....|.|.:|
  Rat   372 FKNDGSVDVGYVQF--NRPFLIFIKDPTNDVPLFLGRVV 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	78/361 (22%)
Serpina1f	NP_001101524.1	serpin	47..410	CDD:422956	79/364 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100