DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and serpinh1b

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001296752.1	Gene:	serpinh1b / 30449	ZFINID:	ZDB-GENE-990415-93	Length:	405	Species:	Danio rerio

Alignment Length:	413	Identity:	102/413 - (24%)
Similarity:	201/413 - (48%)	Gaps:	46/413 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WLS----IILLGVWISAPE--------GLGNTIKDRNLFATELFQTLATDRQDENVIISPVSIQL 56
            |:|    :.||.|.:|..:        .:.:|  ..|| |..|:..:|.::..||::||||.:..
Zfish     2 WVSSLIALCLLAVAVSGEDKKLSTHATSMADT--SANL-AFNLYHNVAKEKGLENILISPVVVAS 63

  Fly    57 ALGLAYYGAEGRTAAELQKTLHASAKESK---DGLAESYHNLLHSYIKSKTVLEIANKVYTRQNL 118
            :||:...|::..||::::..|.|.|.:.:   .||:|....:.....::.| .:|:|::|...::
Zfish    64 SLGMVAMGSKSSTASQVKSVLKADALKDEHLHTGLSELLTEVSDPQTRNVT-WKISNRLYGPSSV 127

  Fly   119 TVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIY 183
            :.:..|.:.::|:::.|...::|..:..|:..||.|..:.|:.|:..:.:.::......:|||::
Zfish   128 SFAEDFVKNSKKHYNYEHSKINFRDKRSAINSINEWAAKTTDGKLPEITKDVKNTDGAMIVNAMF 192

  Fly   184 FKARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFI 248
            ||..|...|:.:...:|.|.::.|.::.||.|.....|.:.:..|.....:.:...:...:|.||
Zfish   193 FKPHWDEKFHHKMVDNRGFLVTRSHTVSVPMMHRTGIYGFYEDTENRFLIVSMPLAHKKSSMIFI 257

  Fly   249 LPNQRSGLQALEQKLKGVDFNLLE----DRW----QWQSVSVYLPKFKFEFDTDLRPTLHKMGIS 305
            :|.....|..||        |||.    |.|    :.::|::.|||...|...||:..|.::|::
Zfish   258 MPYHVEPLDRLE--------NLLTRQQLDTWISKLEERAVAISLPKVSMEVSHDLQKHLGELGLT 314

  Fly   306 -AMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPL-DPKTFVAD 368
             |:....||.|||.....:  .::.|.|.:.::     .:..|..:...:..|..: :||.|.||
Zfish   315 EAVDKSKADLSNISGKKDL--YLSNVFHASSLE-----WDTEGNPFDPSIFGSEKMRNPKLFYAD 372

  Fly   369 HPFAFIIRDK--HAVYFTGHIVK 389
            |||.|:::|.  :::.|.|.:|:
Zfish   373 HPFIFLVKDNKTNSILFIGRLVR 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	94/373 (25%)
serpinh1b	NP_001296752.1	hsp47	28..393	CDD:239001	95/383 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920