DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpinb1a

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001026812.1	Gene:	Serpinb1a / 291091	RGDID:	1306203	Length:	379	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	131/387 - (33%)
Similarity:	198/387 - (51%)	Gaps:	46/387 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NLFATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDGLAESY 92
            :|||.|||.||:......|:..||.||..||.:.:.|.:|.|||:|.||.|..:.|......:|.
  Rat     9 SLFALELFHTLSESSPTGNIFFSPFSISSALAMVFLGTKGTTAAQLSKTFHFDSVEDVHSRFQSL 73

  Fly    93 HNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETE-AVEQINRWVK 156
            :..:.....|.| |::||::|..:.......|....||.:.:::.|:||...:| |.::||:|||
  Rat    74 NAEVSKRGASHT-LKLANRLYGEKTYNFLPEFLTSTQKMYGADLAPVDFQHASEDARKEINQWVK 137

  Fly   157 QQTENKIER-----VVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMF 216
            .|||.||..     ||:|:   |.:.||||||||..|...|..:||.|..|.|::..:..|..|:
  Rat   138 GQTEGKIPELLAVGVVDSM---TKLVLVNAIYFKGMWEEKFMKQDTTDAPFRLNKKNTKSVKMMY 199

  Fly   217 ADNWYYYADYPELDAKAIELFFENINLTMWFILP----NQRSGLQALEQKLKGVDFNLLEDRWQW 277
            ....:::....:|..|.:|:.::...|:|..:||    ::.:||:.:|:::      .||...:|
  Rat   200 QKKKFFFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQI------TLEKLREW 258

  Fly   278 Q--------SVSVYLPKFKFEFDTDLRPTLHKMGISAMF-SDAADFSNIFQDSPIGTR---ITKV 330
            .        .|.|.||:||.|....|...|.::|:..:| |..||.|.:     .|:|   |:|:
  Rat   259 TKRENLENIDVHVKLPRFKIEESYILNSNLGRLGLQDLFNSSKADLSGM-----SGSRDLFISKI 318

  Fly   331 QHKTFIDVNEIGCEAAGASYAAGVP---MSLPLDPKTFVADHPFAFIIRDKHA--VYFTGHI 387
            .||.|::|||.|.|||.|:  ||:.   |.||  .:.|.|||||.|.||....  |.|.|.:
  Rat   319 VHKAFVEVNEEGTEAAAAT--AGIATFCMLLP--EEEFTADHPFIFFIRHNPTANVLFLGRV 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	131/385 (34%)
Serpinb1a	NP_001026812.1	SERPIN	4..379	CDD:294093	131/387 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830