DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpinf2

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001011892.1	Gene:	Serpinf2 / 287527	RGDID:	1306692	Length:	491	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	105/375 - (28%)
Similarity:	177/375 - (47%)	Gaps:	35/375 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SAPEGLGNTIKDRNL------FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAEL 73
            |||    .|.:.|.|      |.|:||..:|......|:::||:|:.|||.....||..:|...|
  Rat    72 SAP----TTEETRRLSQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENL 132

  Fly    74 QKTLHASAKESKDGLAESYHNLLHSYIKSKT--VLEIANKVYTRQNLTVSSHFREVAQKYFDSEV 136
            |:.||.:       :.....:||..:.::..  .:.:|.::|.::...:...|.|.::|.|.::.
  Rat   133 QRVLHMN-------MGSCIPHLLSHFCQNLNPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKP 190

  Fly   137 EPLDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDRE 201
            ..|. .|:.|.:..||:|||:.||.|||..:..|..:|.:.|:|||:|...|...|:...|:...
  Rat   191 VKLT-GRQEEDLMNINKWVKEATEGKIEDFLSELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDS 254

  Fly   202 FWLSESRSIQVPTMFADNW---YYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKL 263
            |.|.|..::.|..|.|.::   ::..:.||:  :.....|:| |::...|:|.. .|....|...
  Rat   255 FHLDEQFTVPVAMMHAQSYPLRWFLLEQPEI--QVAHFPFQN-NMSFVVIMPTY-FGWNVSEVLA 315

  Fly   264 KGVDFNLLEDRWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRIT 328
            ......|.:...:.:...|.|||...|...||..||.|:|:..:| .:.|...|...|.:   ::
  Rat   316 NLTWDTLYQPSMREKPTKVRLPKLHLEQHLDLVATLSKLGLQDLF-QSPDLRGISDQSLV---VS 376

  Fly   329 KVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDK 378
            .|||::.::::|.|.|||.|:..|...|||    .:|..:.||.|.|.::
  Rat   377 SVQHQSTMELSEAGVEAAAATSTAMTRMSL----SSFFLNRPFIFFIMEE 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	100/362 (28%)
Serpinf2	NP_001011892.1	alpha2AP	82..433	CDD:239008	100/361 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010