DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpinf1

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_808788.1	Gene:	Serpinf1 / 287526	RGDID:	631369	Length:	418	Species:	Rattus norvegicus

Alignment Length:	403	Identity:	96/403 - (23%)
Similarity:	179/403 - (44%)	Gaps:	50/403 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 APEGLGNTIKDR----------------NLFATELFQTLATDRQDENVIISPVSIQLALGLAYYG 64
            ||:..|..:.:.                :.|..:|::..:......|:::||:|:..||.....|
  Rat    31 APDSTGEPVVEEDDPFFKAPVNKLAAAVSNFGYDLYRLRSGAVSTGNILLSPLSVATALSALSLG 95

  Fly    65 AEGRTAAELQKTLHASAKESKDGLAESYHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQ 129
            ||.||.:.:.:.|:.....:.| :..:|..||.|....:...:.|:::...:.|.|.|.|
  Rat    96 AEQRTESVIHRALYYDLINNPD-IHSTYKELLASVTAPEKNFKSASRIVFERKLRVKSSF----- 154

  Fly   130 KYFDSEVEPLDFSRETEA----------VEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYF 184
                  |.||:.|..|..          :::||.||:.|.:.||.|....:....::.|:...||
  Rat   155 ------VAPLEKSYGTRPRILTGNPRIDLQEINNWVQAQMKGKIARSTREMPSALSILLLGVAYF 213

  Fly   185 KARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWYY-YADYPELDAKAIELFFENINLTMWFI 248
            |.:||..|:...|..::|.|.|.|:::||.|....... |....:|:.|..:|.... ::::.|.
  Rat   214 KGQWATKFDSRKTTLQDFHLDEDRTVRVPMMSDPKAILRYGLDSDLNCKIAQLPLTG-SMSIIFF 277

  Fly   249 LP-NQRSGLQALEQKLKGVDFNLLEDRWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAA 312
            || .....|..:|:.|.....:.::...:.....:.:||.|..::.|:..:|..|.:.::| ::.
  Rat   278 LPLTVTQNLTMIEESLTSEFVHDIDRELKTIQAVLTVPKLKLSYEGDVTNSLQDMKLQSLF-ESP 341

  Fly   313 DFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRD 377
            |||.| ...|:  ::|:|:|:...:.||.|...:.......|.::.|||   :..:.||.|::||
  Rat   342 DFSKI-TGKPV--KLTQVEHRAAFEWNEEGAGTSSNPDLQPVRLTFPLD---YHLNRPFIFVLRD 400

  Fly   378 KH--AVYFTGHIV 388
            ..  |:.|.|.|:
  Rat   401 TDTGALLFIGRIL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	92/372 (25%)
Serpinf1	NP_808788.1	PEDF	40..415	CDD:239007	93/394 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010