DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpina3n

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_113719.3	Gene:	Serpina3n / 24795	RGDID:	3747	Length:	418	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	118/353 - (33%)
Similarity:	186/353 - (52%)	Gaps:	9/353 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKD-GLAESYH 93
            ||..|::.||....|:||:.||:||..||.:...||:|.:..|:.:.|..:..|:.: .:...:.
  Rat    54 FAFSLYKKLALRNPDKNVVFSPLSISAALAVVSLGAKGNSMEEILEGLKFNLTETPETEIHRGFG 118

  Fly    94 NLLHSYIKSKTVLEIA--NKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVK 156
            :||....:.:..::|:  |.::..:.|.|.:.|:|.|:..:.:|....||.:..||.:.||.:|.
  Rat   119 HLLQRLSQPRDEIQISTGNALFIEKRLQVLAEFQEKAKALYQAEAFTADFQQSREAKKLINDYVS 183

  Fly   157 QQTENKIERVVESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTM-FADNW 220
            :||:.||:.::.:|...|::.|||.||||.:|..||:..||...||:..:.|.::||.| ..|..
  Rat   184 KQTQGKIQGLITNLAKKTSMVLVNYIYFKGKWKVPFDPRDTFQSEFYSGKRRPVKVPMMKLEDLT 248

  Fly   221 YYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDRWQWQSV-SVYL 284
            ..|....||:...:||.:.. |.:..||||:| ..:|.:|..|:.......:|..:...: .:||
  Rat   249 TPYVRDEELNCTVVELKYTG-NASALFILPDQ-GKMQQVEASLQPETLRRWKDSLRPSMIDELYL 311

  Fly   285 PKFKFEFDTDLRPTLHKMGISAMFSDAADFSNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGAS 349
            |||....|.:|...|.::||..:||..||.|.|..|..:  .:::|.||..:||.|.|.|||.|:
  Rat   312 PKFSISADYNLEDVLPELGIKEVFSTQADLSGITGDKDL--MVSQVVHKAVLDVAETGTEAAAAT 374

  Fly   350 YAAGVPMSLPLDPKTFVADHPFAFIIRD 377
            ....||||..|||.....|.||..||.|
  Rat   375 GVKFVPMSAKLDPLIIAFDRPFLMIISD 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	118/353 (33%)
Serpina3n	NP_113719.3	serpinA3_A1AC	37..418	CDD:381019	118/353 (33%)
Serpina3n	NP_113719.3	RCL	367..394		12/26 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010