Protein Alignment Spn43Aa and Serpine1

DIOPT Version :10

• Sequence 1: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_036752.2
• Gene: Serpine1 / 24617
• RGDID: 3249
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 400
• Identity: 103/400 - (25%)
• Similarity: 188/400 - (47%)
• Gaps: 30/400 - (7%)

  Fly     7 IILLGVWISAPEGLGNTIKDRNLFATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAA 71
            :::.|...::|....:|.:....|..::||.:....:|.||:.||..:...|.:......|:|..
  Rat    15 VLVFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQ 79

  Fly    72 ELQKTL--HASAKESKDGLAESYHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDS 134
            ::|..:  :.|.:.:...|.:....|:.|:  :|..:..|:.::.:::|.:...|.....|.|.:
  Rat    80 QIQDAMGFNISERGTAPALRKLSKELMGSW--NKNEISTADAIFVQRDLELVQGFMPHFFKLFRT 142

  Fly   135 EVEPLDFSRETEAVEQINRWVKQQTENKIERVVE--SLEPDTNVALVNAIYFKARWARPFNDEDT 197
            .|:.:|||....|...||.||::.|:..|..::.  ::...|.:.||||:||..:|..||.:..|
  Rat   143 TVKQVDFSEMERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEAST 207

  Fly   198 RDREFWLSESRSIQVPTMFADNWYYYADYPELDA---KAIELFFENINLTMWFILPNQRS-GLQA 258
            ..|.|..|:..:|.||.|..:|.:.|.::...|.   ..:||.:....|:|:...|.::. .|.|
  Rat   208 HQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSA 272

  Fly   259 LEQKLKGVDFNLLEDRWQWQSVS------VYLPKFKFEFDTDLRPTLHKMGISAMFSDA-ADFSN 316
            :...|   |..|:.   ||:|..      :.||||..|.:.|||..|.|:|::.:||.. |||::
  Rat   273 ITNIL---DAELIR---QWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTS 331

  Fly   317 IFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDK--H 379
            :.....:.  :.:...|..|:|||.|   ..||.:..:.:|..:.|...|.|..|.|::|..  .
  Rat   332 LSDQEQLS--VAQALQKVKIEVNESG---TVASSSTAILVSARMAPTEMVLDRSFLFVVRHNPTE 391

  Fly   380 AVYFTGHIVK 389
            .:.|.|.:::
  Rat   392 TILFMGQLME 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	100/379 (26%)
Serpine1	NP_036752.2	serpin	29..402	CDD:476815	101/385 (26%)