DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_035590.1	Gene:	Serpinb9d / 20726	MGIID:	894667	Length:	377	Species:	Mus musculus

Alignment Length:	392	Identity:	116/392 - (29%)
Similarity:	195/392 - (49%)	Gaps:	49/392 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NTIKDRN-LFATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESK 85
            ||:...| .||..|.:.|..|...|||..||:||..||.:...||:|.|..::.:.||.:..|.
Mouse     2 NTLSQANGTFAIHLLKVLCQDNPSENVCFSPMSISSALAMVLLGAKGNTVTQICQALHLNPDED- 65

  Fly    86 DGLAESYHNLLHSYIK---SKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEA 147
              :.:.:..|||:..|   .|..|.:||:::......:...|:|...|::.||:|.|.|:...|.
Mouse    66 --VHQGFQLLLHNLNKPNNQKYCLTMANRLFVENTCELLPTFKESCLKFYHSEMEQLSFAEAAEE 128

  Fly   148 VEQ-INRWVKQQTENKIERVV--ESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRS 209
            ..| ||.||.:||..||..::  :|::..|.:.|.||:||:..|.:.|..:.|::..|.:::..:
Mouse   129 SRQHINMWVSKQTNGKIPDLLPKDSIDSQTRLILANALYFQGTWYKLFEKDSTKEMPFKINKKET 193

  Fly   210 IQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLLEDR 274
            ..|..|:.::.:|:|...|:.|:.:.:.:|.|:|:...:||:            ||||.:.:|:.
Mouse   194 RPVQMMWQEDRFYHAYVKEIQAQVLVMPYEGIDLSFVVLLPD------------KGVDISKVENN 246

  Fly   275 WQWQSVS--------------VYLPKFKFEFDTDLRPTLHKMGISAMFSDA-ADFSNIFQDSPIG 324
            ..::.::              ||||||:.:.|.|:...|..:||..:|..: ||.|.      :.
Mouse   247 LTFEKLTAWTKPDFMNGIELHVYLPKFQLQEDYDMNSLLQHLGILDVFDGSKADLSG------MS 305

  Fly   325 TR----ITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFIIRDK--HAVYF 383
            |:    ::...||..::|||.|.|||.|:....:...|...|:||.|||||.|.|...  :::.|
Mouse   306 TKENLCLSNFVHKCVVEVNEEGTEAAAATAGKTIQCCLGSYPQTFCADHPFLFFIMHSTTNSILF 370

  Fly   384 TG 385
            .|
Mouse   371 CG 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	114/386 (30%)
Serpinb9d	NP_035590.1	serpin	1..377	CDD:393296	116/392 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830