DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and Serpinb5

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001347782.1	Gene:	Serpinb5 / 20724	MGIID:	109579	Length:	375	Species:	Mus musculus

Alignment Length:	377	Identity:	107/377 - (28%)
Similarity:	193/377 - (51%)	Gaps:	41/377 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLH-ASAKESKDGL--AES 91
            ||.:||:.|.......|::.||:.:..:|.||..|.:|.||.|:.:.|| .:.|:...|.  ..|
Mouse    11 FAVDLFKQLCERDPAGNILFSPICLSTSLSLAQVGTKGDTANEIGQVLHFENVKDVPFGFQTVTS 75

  Fly    92 YHNLLHSYIKSKTVLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAVE-QINRWV 155
            ..|.|.|:..    |::..::|..::|..|:.|....::.:..|:|.:||..:.|..: |||..:
Mouse    76 DVNKLSSFYS----LKLVKRLYIDKSLNPSTEFISSTKRPYAKELETVDFKDKLEETKGQINSSI 136

  Fly   156 KQQTENKIERVV--ESLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFAD 218
            |:.|:...|.::  .|:...|.:.:|||.||..:|.:.|.:.:|::..|.:|::.:..|..|..:
Mouse   137 KELTDGHFEDILSENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRISKTDTKPVQMMNLE 201

  Fly   219 NWYYYADYPELDAKAIELFFENINLTMWFILP----NQRSGLQALEQKLKGVDFNLLEDRWQWQS 279
            ..:...:..::..|.|||.|:|.:|:|..:||    ::.:||:.:||:|..      |...||.:
Mouse   202 ATFCLGNIDDISCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEQQLNP------ETLLQWTN 260

  Fly   280 --------VSVYLPKFKFEFDTDLRPTLHKMGISAMFSDA-ADFSNIFQDSPIGTRITKVQHKTF 335
                    |.:.|||||.|...|.:.:|..:|:.::|::: :|||.:.:..  |..::.|.|:..
Mouse   261 PSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETK--GVSLSNVIHRVC 323

  Fly   336 IDVNEIGCEAAGASYAAGVPMSLPLDPK-TFVADHPFAFIIR---DKHAVYF 383
            :::.|.|.|      :..||.|..|..| .|.|||||.:|||   .::.::|
Mouse   324 LEITEDGGE------SIEVPGSRILQHKDEFNADHPFIYIIRHNKTRNIIFF 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	107/377 (28%)
Serpinb5	NP_001347782.1	maspin_like	4..375	CDD:239012	107/377 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930