DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Aa and serpina10b

DIOPT Version :9

Sequence 1:	NP_524805.1	Gene:	Spn43Aa / 45041	FlyBaseID:	FBgn0024294	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_009291625.1	Gene:	serpina10b / 100003661	ZFINID:	ZDB-GENE-100716-5	Length:	395	Species:	Danio rerio

Alignment Length:	401	Identity:	107/401 - (26%)
Similarity:	201/401 - (50%)	Gaps:	36/401 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLGVWISA-------------PEGLGNTIKD---RNL-FATELFQTLATDRQDENVIISPVSIQL 56
            ||.|:|||             |:     |.|   ||. ||..|::.::: ..|.||:.||:|:..
Zfish     5 LLLVFISACFLCSAEHEELRTPD-----ISDLAFRNTDFAINLYRKISS-LHDRNVVFSPLSVST 63

  Fly    57 ALGLAYYGAEGRTAAELQKTLHASAKESKDG--LAESYHNLLHSYIKSKTVLEIANKVYTRQNLT 119
            ........|:|.|..|:.|.|:..|.:..|.  :.|.:.. ||..|..:  :|....::..|:..
Zfish    64 CFSALLLAAQGSTRTEILKGLNLEALDGGDSRRVPELFQQ-LHQNISLQ--MEQGTALFLDQHFH 125

  Fly   120 VSSHFREVAQKYFDSEVEPLDFSRETEAVEQINRWVKQQTENKIERVVESLEPDTNVALVNAIYF 184
            :.::|.:..|::|::||..:|||:.......||.:|.::|..|:..::||:||.|.:.|:|.|::
Zfish   126 LQTNFSQQIQRFFNAEVLRVDFSKPAVCRSLINEFVSRKTGRKVLEMLESVEPLTQMLLLNTIFY 190

  Fly   185 KARWARPFNDEDTRDREFWLSESRSIQVPTMFADNWYYYADYPELDAKAIELFFENINLTMWFIL 249
            |..|.||||..:|....|::.:...:|||.|..:..:...:..:|.|:.:.|.:.. ..:|..:|
Zfish   191 KGDWERPFNPNNTEKSRFYVDKYNIVQVPMMMLEEKFSVVEDRDLRARVLRLPYRG-GASMLILL 254

  Fly   250 PNQRSGLQALEQKLKGVDFNLLEDRWQWQSVSVYLPKFKFEFDTDLRPTLHKMGISAMFSDAADF 314
            |:..:...|:|.::.....:......:...:.|:||:|:.:....:...|.::|||::|.|:||.
Zfish   255 PSADADYTAIEDEISAERLHGWIKNMRRMKMEVHLPRFRMDQSYHMHELLPQLGISSVFQDSADL 319

  Fly   315 SNIFQDSPIGTRITKVQHKTFIDVNEIGCEAAGASYAAGVPMSLPLDPKTFVADHPFAFII--RD 377
            :.:.:|:.:  ::::|.||..|:|.|.|..||.::.......||   |.||:.:.||.|.:  .:
Zfish   320 TGLSRDAHL--KVSQVLHKAVIEVYEQGTSAASSTSVGITAYSL---PDTFIINRPFFFFLYHEE 379

  Fly   378 KHAVYFTGHIV 388
            ..::.|.|.::
Zfish   380 TASLLFMGRVI 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Aa	NP_524805.1	SERPIN	28..387	CDD:238101	97/363 (27%)
serpina10b	XP_009291625.1	Serpin	35..392	CDD:278507	97/366 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910