Protein Alignment Spn43Ab and SERPINB11

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_536723.2
• Gene: SERPINB11 / 89778
• HGNCID: 14221
• Length: 392
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 101/391 - (25%)
• Similarity: 193/391 - (49%)
• Gaps: 49/391 - (12%)

  Fly    35 DLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLR-------LGPGDADAV--- 89
            |::..:.::::.:|:..|..::..::::..:||:|:|..:|::.|.       |.||..|:.
Human    14 DVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKPGFKDSPKCS 78

  Fly    90 ------SQRSGSYQQALTRDNN--FRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYN 146
                  |:....:.|....|:|  ..:||.:|..:.:.|...:...:::.:.:.:..:||... .
Human    79 QAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQS-T 142

  Fly   147 KRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSG 211
            :.|...||..|..|||||:.::.....::..:..|:||.:.:...||..|::.:|.|..|:...|
Human   143 EETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEG 207

  Fly   212 QSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSL--------- 267
            ::|.|:.|:.:..|..|.|.....:|:||||.|...||::|||.....|:.:::.|
Human   208 KNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWT 272

  Fly   268 SGKNLLAEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSR-DGDFGNM---YRMFVSH 328
            |..|       |.:::|||.||:|.:.....|....|.|||..:|:: ..|...|   ..:::|.
Human   273 SSSN-------MMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSK 330

  Fly   329 FINAVEHKANVEVTEAGVDQPLETG---LLKGLFSRSKKFEADHPFVFAIK--YKDSIAFIGHIA 388
            .|    ||:.::|:|.|.:....||   .:|.|..|: :|:|:|||:|.|:  :.::|.|.|.:|
Human   331 AI----HKSYLDVSEEGTEAAAATGDSIAVKSLPMRA-QFKANHPFLFFIRHTHTNTILFCGKLA 390

  Fly   389 N 389
            :
Human   391 S 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	101/391 (26%)
SERPINB11	NP_536723.2	serpinB11_epipin	1..392	CDD:381036	101/391 (26%)
		RCL. /evidence=ECO:0000250	341..365		7/24 (29%)