Protein Alignment Spn43Ab and SERPINE3

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 90/389 - (23%)
• Similarity: 151/389 - (38%)
• Gaps: 81/389 - (20%)

  Fly    33 AADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAV-----SQR 92
            |..||.:|||.....|.|||||.:...:.:...||:|.|..:|          |||:     .:|
Human    34 ALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQL----------ADALGYTVHDKR 88

  Fly    93 SGSYQQAL-------TRDNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNK--R 148
            ...:..|:       ::.....||.::::.........|.:......:|:::..|...|.:.  :
Human    89 VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQ 153

  Fly   149 TADGINRAVATKTNGKITDILRAELLNDRTEG----------------VIVNGVSYSAAWQKAFR 197
            |::|.:|..|.               ...:||                |:|:.:|:...|:|.|.
Human   154 TSEGASRETAG---------------GGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFS 203

  Fly   198 LDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSL---DAKVVELPYQNPDFSMLLLLPNRKD- 258
            ...|:...|....|..::|..|......||.:....   ...|:||||.....|:.|:||..||
Human   204 STDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDT 268

  Fly   259 GLRSLQQSLSGKNLLAEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMF----------- 312
            .|..::..|:...:.....::.:.:::|.||:|.:.....|:......||..:|
Human   269 PLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGIS 333

  Fly   313 SRDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRSKKFEADHPFVFAIK 376
            .:||       .:||..|    |||.:||.|.|......|.||....||...|:||.||::.::
Human   334 GQDG-------FYVSEAI----HKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFIYFLR 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	90/389 (23%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	90/389 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		8/45 (18%)