DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and serping1

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_005166940.3	Gene:	serping1 / 567801	ZFINID:	ZDB-GENE-030131-1262	Length:	652	Species:	Danio rerio

Alignment Length:	396	Identity:	96/396 - (24%)
Similarity:	176/396 - (44%)	Gaps:	56/396 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SKTVGYDAAADRNLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLG 82
            ||.:..::..|   .:..:|:.:.......|::.||.:|.::::...:||:|:|...|:..|.|.
Zfish   288 SKAILQESLGD---FSTSVYSRLKGSKAKANLIFSPISIAAALSNLLLGARGKTRMHLEGALGLP 349

  Fly    83 PGDA---DAVSQRSGSYQQALTRDNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPP 144
            .|.:   ..:.:..|..:..|      ::|:.|:.|...:...:|.:.::..:       :|.|
Zfish   350 LGFSCLHTELKKLRGVMKDTL------KMASAIFYNPEQQLAEAFINQSKEFY-------EFVP- 400

  Fly   145 YNKRTADG------INRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEK 203
             .|.|.|.      ||:.|..|||.|||.::  :.::..|..|::|.|.::..|:..|. ....|
Zfish   401 -QKLTNDSTRNVALINKWVENKTNKKITQLI--DDVDPSTTFVLLNAVYFNGKWKTVFE-STNNK 461

  Fly   204 RSFRTGSGQSVKVDTMWT---LQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPN--RKDGLRSL 263
            ..|...||::..|.|:::   :....|.:....|.....|..||   |:.:|:|.  .::....:
Zfish   462 EKFTMFSGETKDVKTLYSSNYILQMGYNKQLKADVGKFPLTGQN---SLYILVPRTLSEESFLLM 523

  Fly   264 QQSLSGKNLLAEIGAMSQ---QKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMF 325
            :.:::...|...:..|:|   |..||.||...:|....::...:.:|:..:|:..    |:..||
Zfish   524 ENNINRNTLEEMVSEMNQTPAQSAEVTLPAIKLTMTTQVDDLLRNMGLSDLFNNP----NLCGMF 584

  Fly   326 VSH---FINAVEHKANVEVTEAGVDQPLETGLLKGLFSRS-KKFEADHPFVFAIKYKDSIA---F 383
            ...   ||:.|.|:|.:.:||.||:....|.:   .|||| ..|.|..|||. |.:.|..|   |
Zfish   585 PGEPESFISDVRHRAFLSLTEKGVEAAAATSI---SFSRSFSSFSALQPFVL-ILWSDEAAVPLF 645

  Fly   384 IGHIAN 389
            :|.|.|
Zfish   646 MGRIIN 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	91/380 (24%)
serping1	XP_005166940.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100