DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ab and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_001027395.1	Gene:	Spn43Ab / 45040	FlyBaseID:	FBgn0024293	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	385	Identity:	89/385 - (23%)
Similarity:	164/385 - (42%)	Gaps:	45/385 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 NLLAADLYNAV--AADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQR 92
            |..|..||..|  :.|:.::|:..||.::..:::...:||.|.|..:|..|  :|.......::.
Zfish    41 NDFAFHLYKRVIESPDYQSKNIFFSPFSVSIALSELSLGAGGDTKQQLLSG--IGYNSTTFSTEE 103

  Fly    93 SGSYQQALTRDNNFR------LANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTAD 151
            ......:|..|...|      :...:|.::..:....|.:..:..:.|:...:||..   |.|.|
Zfish   104 MHQLFHSLLEDIGNRTGVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDGFTVDFRV---KETVD 165

  Fly   152 GINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSGQSVKV 216
            .||.....||.||....:  :.|.:.|...::..:.:...|.|.|:.:||.:.:|......:|.|
Zfish   166 QINNYAKKKTQGKFNQAV--DDLEEDTLMFLLTYIYFKGKWDKPFKPEKTRESTFHIDDKTTVPV 228

  Fly   217 DTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRK---DGLRSLQQSLSGKNLLAEIGA 278
            ..|...:.........|..||:.|.|:: .|||.|.:|:.|   ..::.|:.::|.::......:
Zfish   229 QMMHQYERLKVFYDAELSTKVLCLDYKD-SFSMFLAVPDDKMEHKNIKDLEMTVSRQHFEKWRRS 292

  Fly   279 MSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSRDGDFGNMYRMFVSHFINAVEHKANVEVTE 343
            ..::.|::.:||.|:.....|:...|.:|:..|||...:|..:....:  |::.|.|||.:::.|
Zfish   293 AFKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKANFTGVSEEKI--FVSKVLHKATLDIDE 355

  Fly   344 AGVDQPLETG------------LLKGLFSRSKKFEADHPFVFAI--KYKDSIAFIGHIAN 389
            .|......||            :||  |:|        ||:..|  :..|:|.|.|.:.|
Zfish   356 QGTTAAAVTGVSMRVRLHNPLSILK--FNR--------PFMVFITDQTNDNILFFGKVVN 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	SERPIN	30..387	CDD:238101	88/381 (23%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	88/381 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110