Protein Alignment Spn43Ab and SERPINB13

DIOPT Version :10

• Sequence 1: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 103/401 - (25%)
• Similarity: 180/401 - (44%)
• Gaps: 55/401 - (13%)

  Fly    32 LAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQ---------GLRLGPGDAD 87
            |..||:..:...: :.|:..||..|.:::.:..:|.:|.|||:|::         ..|:...:.:
Human    11 LGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKE 74

  Fly    88 AV---------SQRSGSYQQ---------ALTRDNNFRLANNIYINENLEFKGSFRDVAQRQFDS 134
            .|         ......:||         .||.|....:.|.::..:...|...:.|..::.:.:
Human    75 VVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 139

  Fly   135 NIDKLDFHPPYNKRTAD----GINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKA 195
            :::.:||     ...||    .||..|.:|||.||.|:.....::..|:.|:||.|.:...|.:.
Human   140 SLEPVDF-----VNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 199

  Fly   196 FRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGL 260
            |:.:.|::..|......|..|..|....:|::..:..|.||::.:||:|.|.||.:||||..|||
Human   200 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGL 264

  Fly   261 RSLQQSLSGKNLL--AEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFS-RDGDFGNMY 322
            ..:...:|.:.|:  ...|.|.::||.:.||:|.|..|..||.....:|:...|| ...|:..|.
Human   265 EKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMS 329

  Fly   323 R---MFVSHFINAVEHKANVEVTEAGVDQPLETGLLKGLFSRS----KKFEADHPFVFAIKYKD- 379
            .   ::...|:    |.:.|.|||.|.:....||:  |....|    :....:|||:|.|::.:
Human   330 SGSGLYAQKFL----HSSFVAVTEEGTEAAAATGI--GFTVTSAPGHENVHCNHPFLFFIRHNES 388

  Fly   380 -SIAFIGHIAN 389
             ||.|.|..::
Human   389 NSILFFGRFSS 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	103/401 (26%)
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	103/401 (26%)